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Guidelines

MIRAGE

LSM10, U7 small nuclear RNA associated

Summary

Gene Symbol

LSM10

Organism

Homo sapiens (human)

External Links

NCBI Gene

84967

PubChem

84967

Alliance of Genome Resources

HGNC:17562

JoGo

LSM10

TogoVar

LSM10

Annotation

Keyword

3D-structure
Nucleus
Proteomics identification
RNA-binding
Reference proteome
Ribonucleoprotein
mRNA splicing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q969L4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mRNA 3'-end processing by stem-loop binding and cleavage	IBA
RNA splicing	IEA
positive regulation of G1/S transition of mitotic cell cycle	IMP	16914750

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

RNA splicing

RNA 3'-end processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

histone mRNA metabolic process [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

RNA splicing

RNA 3'-end processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

histone mRNA metabolic process [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

RNA splicing

RNA 3'-end processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

histone mRNA metabolic process [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

RNA splicing

RNA 3'-end processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

histone mRNA metabolic process [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

RNA splicing

RNA 3'-end processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

histone mRNA metabolic process [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

RNA splicing

RNA 3'-end processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

histone mRNA metabolic process [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

RNA splicing

RNA 3'-end processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

histone mRNA metabolic process [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

RNA splicing

RNA 3'-end processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

histone mRNA metabolic process [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

RNA splicing

RNA 3'-end processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

histone mRNA metabolic process [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

RNA splicing

RNA 3'-end processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA 3'-end processing [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

histone mRNA metabolic process [inference]

mRNA 3'-end processing by stem-loop binding and cleavage

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle process [inference]

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle phase transition [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle G1/S phase transition [inference]

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleoplasm	TAS
nucleoplasm	IDA
U7 snRNP	IDA	11574479
Cajal body	IDA	11574479
nuclear body	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

Sm-like protein family complex [inference]

small nuclear ribonucleoprotein complex [inference]

U7 snRNP

nuclear protein-containing complex [inference]

small nuclear ribonucleoprotein complex [inference]

U7 snRNP

ribonucleoprotein complex [inference]

small nuclear ribonucleoprotein complex [inference]

U7 snRNP

cytoplasmic U snRNP body

cellular anatomical entity [inference]

nucleoplasm

Cajal body

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	12975319 15231747 16087681 16189514 19060904 33961781
histone pre-mRNA DCP binding	ISS
histone pre-mRNA DCP binding	IBA
U7 snRNA binding	IBA
U7 snRNA binding	IPI	18082603

GO Hierarchy

molecular function

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

snRNA binding [inference]

U7 snRNA binding

histone pre-mRNA DCP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

u7 snRNA-associated Sm-like protein LSm10

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
U7 snRNA binding
histone pre-mRNA DCP binding
mRNA 3'-end processing by stem-loop binding and cleavage

Displaying **all 3** entries
InterPro
LSM domain superfamily
Sm domain, eukaryotic/archaea-type
Sm domain

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026