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hydroxymethylglutaryl-CoA reductase (NADPH) HMG2

Summary

Gene Symbol

HMG2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

851171

PubChem

851171

Alliance of Genome Resources

SGD:S000004442

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
NADP
Nucleus
Oxidoreductase
Phosphoprotein
Reference proteome
Sterol biosynthesis
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P12684

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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Last »
GO Term	Evidence Code	PMID
ergosterol biosynthetic process	ISA	3526336
ergosterol biosynthetic process	IDA	3526336
ergosterol biosynthetic process	IBA
isoprenoid biosynthetic process	IBA
isoprenoid biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

isoprenoid biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

ergosterol metabolic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

sterol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

isoprenoid biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

ergosterol metabolic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

secondary alcohol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

sterol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

isoprenoid biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

ergosterol metabolic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

sterol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

isoprenoid biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

secondary alcohol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

sterol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

ergosterol metabolic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

Displaying entries **1 - 5** of 13 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
proteasome complex	IPI	27226596
nucleus	IEA
nuclear envelope	IDA	8744950
nuclear envelope	IEA
peroxisomal membrane	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

proteasome complex

catalytic complex [inference]

peptidase complex [inference]

endopeptidase complex [inference]

proteasome complex

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

nuclear periphery

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

microbody membrane [inference]

peroxisomal membrane

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

microbody membrane [inference]

peroxisomal membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
hydroxymethylglutaryl-CoA reductase (NADPH) activity	IDA	3526336
hydroxymethylglutaryl-CoA reductase (NADPH) activity	IGI	2828155
hydroxymethylglutaryl-CoA reductase (NADPH) activity	IBA
hydroxymethylglutaryl-CoA reductase (NADPH) activity	IEA
oxidoreductase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

hydroxymethylglutaryl-CoA reductase (NADPH) activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 5** entries
Location	References
proteasome complex	PMID:27226596
nuclear periphery	PMID:22842922
endoplasmic reticulum membrane	PMID:8744950
nuclear envelope	PMID:8744950
endoplasmic reticulum	PMID:26928762 PMID:8744950

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