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dolichyl-phosphate-mannose-protein mannosyltransferase PMT2

Summary

Gene Symbol

PMT2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

851210

KEGG Gene ID

sce:YAL023C

PubChem

851210

Alliance of Genome Resources

SGD:S000000021

Annotation

Keyword

3D-structure
Acetylation
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Phosphoprotein
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P31382

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
protein O-linked glycosylation	IEA IMP	9184828
ERAD pathway	IGI IMP	18182384 21147851
regulation of endoplasmic reticulum unfolded protein response	IGI IMP	21231968 23704572
protein exit from endoplasmic reticulum	IGI	21147851
protein glycosylation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

mannosylation [inference]

protein mannosylation [inference]

protein O-linked mannosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

cell wall organization or biogenesis [inference]

cell wall biogenesis [inference]

fungal-type cell wall biogenesis

fungal-type cell wall organization or biogenesis [inference]

fungal-type cell wall biogenesis

cellular component organization or biogenesis [inference]

cellular component biogenesis [inference]

cell wall biogenesis [inference]

fungal-type cell wall biogenesis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

ERAD pathway

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response

Displaying **all 5** entries
GO Term	Evidence Code	PMID
dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex	IDA	12551906
endoplasmic reticulum	HDA IBA IEA	26928762
endoplasmic reticulum membrane	IEA
dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex	IDA IPI	12551906 21956107 8543034
membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

dolichyl-phosphate-mannose-protein mannosyltransferase complex [inference]

endoplasmic reticulum protein-containing complex [inference]

dolichyl-phosphate-mannose-protein mannosyltransferase complex [inference]

intracellular protein-containing complex [inference]

mannosyltransferase complex [inference]

dolichyl-phosphate-mannose-protein mannosyltransferase complex [inference]

catalytic complex [inference]

transferase complex [inference]

mannosyltransferase complex [inference]

dolichyl-phosphate-mannose-protein mannosyltransferase complex [inference]

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 3** entries
GO Term	Evidence Code	PMID
glycosyltransferase activity	IEA
dolichyl-phosphate-mannose-protein mannosyltransferase activity	IBA IDA IEA IGI IMP	21956107 7852348 8543034
mannosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

hexosyltransferase activity [inference]

mannosyltransferase activity

dolichyl-phosphate-mannose-protein mannosyltransferase activity

catalytic activity, acting on a protein [inference]

dolichyl-phosphate-mannose-protein mannosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00728

Name

dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109]

References

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R07620	2.4.1.109	G74840NI	G61491DK

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
endoplasmic reticulum	PMID:26928762
dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex	PMID:12551906 PMID:21956107 PMID:8543034
dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex	PMID:12551906

Disease

Disease Ontology

Displaying **all 8** entries
DO ID	Disease Name	Source
DOID:0050453	lissencephaly	Alliance of Genome Resources
DOID:0050560	Walker-Warburg syndrome	Alliance of Genome Resources
DOID:0110274	autosomal recessive limb-girdle muscular dystrophy	Alliance of Genome Resources
DOID:0110298	autosomal recessive limb-girdle muscular dystrophy type 2N	Alliance of Genome Resources
DOID:0111240	congenital muscular dystrophy-dystroglycanopathy type A2	Alliance of Genome Resources
DOID:0112374	muscular dystrophy-dystroglycanopathy	Alliance of Genome Resources
DOID:0112380	muscular dystrophy-dystroglycanopathy type B2	Alliance of Genome Resources
DOID:9884	muscular dystrophy	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007487
Gene Name: dolichyl-phosphate-mannose-protein mannosyltransferase PMT2

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	31024	FB:FBgn0086368
Danio rerio	563878	ZFIN:ZDB-GENE-070112-1002
Xenopus tropicalis	100490100	Xenbase:XB-GENE-1006906
Homo sapiens	29954	HGNC:19743
Mus musculus	217734	MGI:2444430
Rattus norvegicus	688673	RGD:1586427