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protein phosphatase regulator SHP1

Summary

Gene Symbol

SHP1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

852222

PubChem

852222

Alliance of Genome Resources

SGD:S000000154

Annotation

Keyword

3D-structure
Cytoplasm
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
P34223	Suppressor of high-copy PP1 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
proteasome-mediated ubiquitin-dependent protein catabolic process	IBA IMP	15258615
glycogen metabolic process	IMP	7891699
ERAD pathway	IMP	21148305
sister chromatid biorientation	IMP	20483956
nuclear membrane reassembly	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

cellular process [inference]

cell cycle process [inference]

attachment of spindle microtubules to kinetochore [inference]

sister chromatid biorientation

meiotic cell cycle process [inference]

ascospore formation

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular developmental process [inference]

cell development [inference]

ascospore formation

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy [inference]

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

Golgi organization

vacuole organization [inference]

autophagosome organization [inference]

autophagosome assembly

organelle assembly [inference]

autophagosome assembly

cellular component assembly [inference]

organelle assembly [inference]

autophagosome assembly

membrane assembly [inference]

nuclear membrane reassembly

membrane organization [inference]

membrane fusion

membrane assembly [inference]

nuclear membrane reassembly

nuclear membrane organization [inference]

nuclear membrane reassembly

reproductive process [inference]

developmental process involved in reproduction [inference]

sexual sporulation [inference]

sexual sporulation resulting in formation of a cellular spore [inference]

ascospore formation

reproductive process in single-celled organism [inference]

ascospore formation

meiotic cell cycle process [inference]

ascospore formation

developmental process [inference]

developmental process involved in reproduction [inference]

sexual sporulation [inference]

sexual sporulation resulting in formation of a cellular spore [inference]

ascospore formation

sporulation [inference]

sporulation resulting in formation of a cellular spore [inference]

sexual sporulation resulting in formation of a cellular spore [inference]

ascospore formation

sexual sporulation [inference]

sexual sporulation resulting in formation of a cellular spore [inference]

ascospore formation

anatomical structure formation involved in morphogenesis [inference]

sporulation resulting in formation of a cellular spore [inference]

sexual sporulation resulting in formation of a cellular spore [inference]

ascospore formation

anatomical structure development [inference]

cell development [inference]

ascospore formation

cellular developmental process [inference]

cell development [inference]

ascospore formation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

ERAD pathway

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	HDA IBA IEA	14562095 26928762
cytosol	HDA IBA	26928762
cytoplasm	HDA IEA	14562095

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein phosphatase regulator activity	IMP	23418575 7891699
ubiquitin binding	IBA
K48-linked polyubiquitin modification-dependent protein binding	IDA	28525741

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

ubiquitin-like protein binding [inference]

ubiquitin binding

modification-dependent protein binding [inference]

polyubiquitin modification-dependent protein binding [inference]

K48-linked polyubiquitin modification-dependent protein binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

phosphatase regulator activity [inference]

protein phosphatase regulator activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
cytosol	PMID:26928762
nucleus	PMID:14562095 PMID:26928762
cytoplasm	PMID:14562095

Ortholog

Displaying entries **1 - 10** of 16 in total

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	177057	WB:WBGene00022381
Drosophila melanogaster	35674	FB:FBgn0033179
Drosophila melanogaster	37897	FB:FBgn0259729
Danio rerio	492805	ZFIN:ZDB-GENE-041114-160
Danio rerio	100537478	ZFIN:ZDB-GENE-110411-202
Xenopus tropicalis	448090	Xenbase:XB-GENE-972873
Xenopus tropicalis	101733824	Xenbase:XB-GENE-13579709
Homo sapiens	55968	HGNC:15912
Homo sapiens	137886	HGNC:27035
Homo sapiens	165324	HGNC:27265