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type I sorting receptor

Summary

Gene Symbol

PEP1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

852264

PubChem

852264

Alliance of Genome Resources

SGD:S000000113

Annotation

Keyword

Glycoprotein
Golgi apparatus
Nucleotide-binding
Protein transport
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P32319	Carboxypeptidase Y receptor Carboxypeptidase Y-deficient protein 1 Sortilin VPS10 Vacuolar carboxypeptidase sorting receptor VPS10 Vacuolar protein sorting-associated protein 10 Vacuolar protein-targeting protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein transport	IEA
mitophagy	IMP	31332264
Golgi to endosome transport	IBA
vacuolar transport	IEA IMP	8187177
vesicle targeting, trans-Golgi to endosome

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion [inference]

mitophagy

macroautophagy [inference]

autophagy of peroxisome [inference]

pexophagy

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion [inference]

mitophagy

macroautophagy [inference]

autophagy of peroxisome [inference]

pexophagy

cellular process [inference]

vesicle targeting [inference]

vesicle targeting, to, from or within Golgi [inference]

vesicle targeting, trans-Golgi to endosome

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion [inference]

mitophagy

macroautophagy [inference]

autophagy of peroxisome [inference]

pexophagy

cellular localization [inference]

intracellular transport [inference]

vacuolar transport

Golgi to vacuole transport

cytosolic transport [inference]

Golgi to endosome transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

process utilizing autophagic mechanism [inference]

autophagy [inference]

autophagy of mitochondrion [inference]

mitophagy

macroautophagy [inference]

autophagy of peroxisome [inference]

pexophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

autophagy of mitochondrion [inference]

mitophagy

organelle disassembly [inference]

autophagy of mitochondrion [inference]

mitophagy

cellular component disassembly [inference]

organelle disassembly [inference]

autophagy of mitochondrion [inference]

mitophagy

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport [inference]

intracellular transport [inference]

vacuolar transport

Golgi to vacuole transport

cytosolic transport [inference]

Golgi to endosome transport

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport

Golgi to vacuole transport

cytosolic transport [inference]

Golgi to endosome transport

cellular localization [inference]

intracellular transport [inference]

vacuolar transport

Golgi to vacuole transport

cytosolic transport [inference]

Golgi to endosome transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	IBA IEA
Golgi apparatus	IBA IDA IEA	20936498
fungal-type vacuole	HDA	26928762
cytosol	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

storage vacuole [inference]

fungal-type vacuole

lytic vacuole [inference]

fungal-type vacuole

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

storage vacuole [inference]

fungal-type vacuole

lytic vacuole [inference]

fungal-type vacuole

Golgi apparatus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
signal sequence binding	IMP	8187177
nucleotide binding	IEA

GO Hierarchy

molecular function

binding [inference]

amide binding [inference]

peptide binding [inference]

signal sequence binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sortilin

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
Sortilin, C-terminal
Sortilin, N-terminal
VPS10
WD40/YVTN repeat-like-containing domain superfamily

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
fungal-type vacuole	PMID:26928762
Golgi apparatus	PMID:20936498

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10652	Alzheimer's disease	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 47 in total

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Species	Gene ID	OrthoDB
Torulaspora delbrueckii	11504239	4950_0:000edf
Torulaspora delbrueckii	11504735	4950_0:000577
Naumovozyma castellii CBS 4309	11525050	1064592_0:0008ad
Tetrapisispora phaffii CBS 4417	11533736	1071381_0:000d1d
Kazachstania africana CBS 2517	13885195	1071382_0:000850
Tetrapisispora blattae CBS 6284	14493335	1071380_0:00035f
Eremothecium sinecaudum	28725188	45286_0:000be1
Saccharomyces eubayanus	28929300	1080349_0:0001ff
Kazachstania naganishii CBS 8797	34526926	1071383_0:000d2b
Lachancea lanzarotensis	34683566	1245769_0:00031d

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements