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phosphatidate cytidylyltransferase

Summary

Gene Symbol

CDS1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

852317

KEGG Gene ID

sce:YBR029C

PubChem

852317

Alliance of Genome Resources

SGD:S000000233

Annotation

Keyword

Cytoplasmic vesicle
Endoplasmic reticulum
Magnesium
Nucleotidyltransferase
Phospholipid biosynthesis
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P38221	CDP-diacylglycerol synthase CDP-diglyceride pyrophosphorylase CDP-diglyceride synthase CTP:phosphatidate cytidylyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
CDP-diacylglycerol biosynthetic process	IEA IMP	2832385
phospholipid biosynthetic process	IEA
phosphatidylserine metabolic process	IMP	2832385
phosphatidylinositol metabolic process	IMP	2832385 8557688

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasmic vesicle	IEA
membrane	IEA
endoplasmic reticulum membrane	IBA IEA
Golgi to plasma membrane transport vesicle	IDA	2163397
endoplasmic reticulum	HDA IDA IEA	23623749 26928762 8557688

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
phosphatidate cytidylyltransferase activity	IDA IEA	8557688
nucleotidyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity

cytidylyltransferase activity [inference]

phosphatidate cytidylyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

PHOSPHATIDATE CYTIDYLYLTRANSFERASE

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
CDP-diacylglycerol biosynthetic process
lipid metabolic process
nucleotidyltransferase activity
phosphatidate cytidylyltransferase activity
phospholipid biosynthetic process
transferase activity, transferring phosphorus-containing groups
transferase activity

Displaying **all 2** entries
InterPro
Phosphatidate cytidylyltransferase, eukaryota
Phosphatidate cytidylyltransferase

KEGG BRITE Database

Orthology

K00981

Name

phosphatidate cytidylyltransferase [EC:2.7.7.41]

References

9085581

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
Golgi to plasma membrane transport vesicle	PMID:2163397
endoplasmic reticulum	PMID:23623749 PMID:26928762 PMID:8557688

Rhea

RHEA:16229

H⁺ + CTP + a 1,2-diacyl-sn-glycero-3-phosphate

diphosphate + a CDP-1,2-diacyl-sn-glycerol

Enzyme

2.7.7.41

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:162	cancer	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007216
Gene Name: phosphatidate cytidylyltransferase

Ortholog

Displaying entries **1 - 10** of 34 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	1040		HGNC:1800
Homo sapiens	8760		HGNC:1801
Drosophila melanogaster	43950		FB:FBgn0010350
Mus musculus	74596		MGI:1921846
Rattus norvegicus	81925		RGD:621185
Mus musculus	110911		MGI:1332236
Rattus norvegicus	114101		RGD:621186
Danio rerio	394161		ZFIN:ZDB-GENE-030717-4
Kluyveromyces lactis	2895206	28985_0:0011e5
Caenorhabditis elegans	3565046		WB:WBGene00016384

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements