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phosphatidate cytidylyltransferase

Summary

Gene Symbol

CDS1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

852317

KEGG Gene ID

sce:YBR029C

PubChem

852317

Alliance of Genome Resources

SGD:S000000233

Annotation

Keyword

Cytoplasmic vesicle
Endoplasmic reticulum
Magnesium
Nucleotidyltransferase
Phospholipid biosynthesis
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P38221	CDP-diacylglycerol synthase CDP-diglyceride pyrophosphorylase CDP-diglyceride synthase CTP:phosphatidate cytidylyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
CDP-diacylglycerol biosynthetic process	IEA IMP	2832385
phosphatidylserine metabolic process	IMP	2832385
phospholipid biosynthetic process	IEA
phosphatidylinositol metabolic process	IMP	2832385 8557688

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

CDP-diacylglycerol metabolic process [inference]

CDP-diacylglycerol biosynthetic process

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

phosphatidylinositol metabolic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

CDP-diacylglycerol biosynthetic process

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
endoplasmic reticulum	HDA IDA IEA	23623749 26928762 8557688
transport vesicle	IEA
endoplasmic reticulum membrane	IBA IEA
Golgi to plasma membrane transport vesicle	IDA	2163397
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

Golgi to plasma membrane transport vesicle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
phosphatidate cytidylyltransferase activity	IDA IEA	8557688
nucleotidyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity

cytidylyltransferase activity [inference]

phosphatidate cytidylyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00981

Name

phosphatidate cytidylyltransferase [EC:2.7.7.41]

References

9085581

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
endoplasmic reticulum	PMID:23623749 PMID:26928762 PMID:8557688
Golgi to plasma membrane transport vesicle	PMID:2163397

Rhea

RHEA:16229

H⁺ + CTP + a 1,2-diacyl-sn-glycero-3-phosphate

diphosphate + a CDP-1,2-diacyl-sn-glycerol

Enzyme

2.7.7.41

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:162	cancer	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007216
Gene Name: phosphatidate cytidylyltransferase

Ortholog

Displaying entries **1 - 10** of 12 in total

1

2

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	3565046	WB:WBGene00016384
Drosophila melanogaster	43950	FB:FBgn0010350
Danio rerio	394161	ZFIN:ZDB-GENE-030717-4
Danio rerio	100002015	ZFIN:ZDB-GENE-070705-78
Xenopus tropicalis	100144929	Xenbase:XB-GENE-986549
Xenopus tropicalis	100496577	Xenbase:XB-GENE-978567
Homo sapiens	1040	HGNC:1800
Homo sapiens	8760	HGNC:1801
Mus musculus	74596	MGI:1921846
Mus musculus	110911	MGI:1332236

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GlycoPOST

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Tools

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Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements