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N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase anchoring subunit ALG14

Summary

Gene Symbol

ALG14

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

852362

KEGG Gene ID

sce:YBR070C

PubChem

852362

Alliance of Genome Resources

SGD:S000000274

Annotation

Keyword

Endoplasmic reticulum
Nucleus
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P38242	Asparagine-linked glycosylation protein 14

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
dolichol-linked oligosaccharide biosynthetic process	IBA IDA IEA IMP IPI	15615718 16100110 16100113

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
nuclear outer membrane-endoplasmic reticulum membrane network	IDA	15282802
membrane	IEA
nuclear membrane	IEA
peroxisome	HDA	35563734

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

UDP-N-acetylglucosamine transferase complex

endoplasmic reticulum protein-containing complex [inference]

UDP-N-acetylglucosamine transferase complex

catalytic complex [inference]

UDP-N-acetylglucosamine transferase complex

cellular anatomical entity [inference]

organelle membrane [inference]

nuclear outer membrane-endoplasmic reticulum membrane network

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of Golgi membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity	IBA
protein-membrane adaptor activity	IMP	16100110 16100113

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

protein-membrane adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K07441

Name

beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141]

References

16100110

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05970	2.4.1.141	G68544GH	G05026ZL

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
UDP-N-acetylglucosamine transferase complex	PMID:16100110 PMID:16100113
peroxisome	PMID:35563734
endoplasmic reticulum membrane	PMID:16100110 PMID:17686769
nuclear outer membrane-endoplasmic reticulum membrane network	PMID:15282802

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110658	congenital myasthenic syndrome 15	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007381
Gene Name: N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase anchoring subunit ALG14

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	187398	WB:WBGene00019725
Drosophila melanogaster	32479	FB:FBgn0030645
Danio rerio	450072	ZFIN:ZDB-GENE-041010-195
Xenopus tropicalis	100379745	Xenbase:XB-GENE-983948
Homo sapiens	199857	HGNC:28287
Mus musculus	66789	MGI:1914039
Rattus norvegicus	362031	RGD:1312003

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024