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dolichyl-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-dolichol alpha-1,2- glucosyltransferase

Summary

Gene Symbol

DIE2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

853142

KEGG Gene ID

sce:YGR227W

PubChem

853142

Alliance of Genome Resources

SGD:S000003459

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P50076	Alpha-1,2-glucosyltransferase ALG10-A Alpha-2-glucosyltransferase ALG10 Asparagine-linked glycosylation protein 10 Dolichyl-phosphoglucose-dependent glucosyltransferase ALG10

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein glycosylation	IEA
protein N-linked glycosylation	IBA IMP	9597543
dolichol-linked oligosaccharide biosynthetic process	IEA TAS	10336995

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	IEA
endoplasmic reticulum membrane	IEA IMP	9597543
endoplasmic reticulum	HDA IBA IEA	26928762
cell periphery	HDA	26928762

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

cell periphery

Displaying **all 3** entries
GO Term	Evidence Code	PMID
dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity	IBA IDA IEA	9597543
glycosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

hexosyltransferase activity [inference]

glucosyltransferase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
dolichol-linked oligosaccharide biosynthetic process
dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity
protein N-linked glycosylation
transferase activity

Displaying 1 entry
InterPro
Alpha-2-glucosyltransferase Alg10

KEGG BRITE Database

Orthology

K03850

Name

alpha-1,2-glucosyltransferase [EC:2.4.1.256]

References

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R06264	2.4.1.- 2.4.1.256	G71142DF G98256YA	G72079JG

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
cell periphery	PMID:26928762
endoplasmic reticulum	PMID:26928762

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050563	nonsyndromic deafness	Alliance of Genome Resources
DOID:0110645	long QT syndrome 2	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007336
Gene Name: dolichyl-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-dolichol alpha-1,2- glucosyltransferase

Ortholog

Displaying entries **11 - 20** of 30 in total

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Species	Gene ID	OrthoDB
Zygosaccharomyces rouxii	8202769	4956_0:0004ac
Lachancea thermotolerans CBS 6340	8291165	559295_0:000324
Eremothecium cymbalariae DBVPG#7215	11470489	931890_0:0002dc
Naumovozyma dairenensis CBS 421	11495069	1071378_0:0008fd
Torulaspora delbrueckii	11504549	4950_0:001050
Naumovozyma castellii CBS 4309	11527425	1064592_0:00103f
Tetrapisispora phaffii CBS 4417	11532769	1071381_0:000108
Kazachstania africana CBS 2517	13883257	1071382_0:00060e
Tetrapisispora blattae CBS 6284	14493793	1071380_0:0007a9
Eremothecium sinecaudum	28721783	45286_0:000245

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements