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GTPase-activating protein BUD2

Summary

Gene Symbol

BUD2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

853770

PubChem

853770

Alliance of Genome Resources

SGD:S000001575

Annotation

Keyword

Acetylation
GTPase activation
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P33314	Bud site selection protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
invasive growth in response to glucose limitation	IMP	23783029
axial cellular bud site selection	IMP	2065354 22558355
bipolar cellular bud site selection	IMP	2065354
establishment or maintenance of cell polarity	IMP	23783029
signal transduction	IEA

GO Hierarchy

biological process

reproduction [inference]

asexual reproduction [inference]

cell budding [inference]

reproduction of a single-celled organism [inference]

cell budding [inference]

cellular process [inference]

establishment or maintenance of cell polarity

establishment of cell polarity [inference]

cellular bud site selection [inference]

signal transduction

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

cell cycle process [inference]

mitotic cell cycle process [inference]

cellular bud site selection [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

cell division [inference]

cell budding [inference]

growth [inference]

filamentous growth

filamentous growth of a population of unicellular organisms [inference]

growth of unicellular organism as a thread of attached cells [inference]

invasive filamentous growth

invasive growth in response to glucose limitation

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of cellular process [inference]

signal transduction

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of exit from mitosis [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of exit from mitosis [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

spindle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle orientation checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of exit from mitosis [inference]

mitotic spindle orientation checkpoint signaling

Displaying **all 5** entries
GO Term	Evidence Code	PMID
incipient cellular bud site	IDA	10444589
prospore membrane	HDA	24390141
cytoplasm	HDA	14562095
cellular bud neck	IDA	10444589
cellular bud neck	HDA	14562095

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

incipient cellular bud site

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

prospore membrane

site of polarized growth [inference]

cellular bud neck

Displaying **all 2** entries
GO Term	Evidence Code	PMID
GTPase activator activity	IDA	8371782
GTPase activator activity	IEA

GO Hierarchy

molecular function

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

GTPase

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying 1 entry
Gene Ontology
negative regulation of Ras protein signal transduction

Displaying **all 4** entries
InterPro
Ras GTPase-activating domain
Ras GTPase-activating protein, conserved site
RasGAP protein, C-terminal
Rho GTPase activation protein

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
prospore membrane	PMID:24390141
incipient cellular bud site	PMID:10444589
cytoplasm	PMID:14562095
cellular bud neck	PMID:10444589 PMID:14562095

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	5921	FB:FBgn0003969
Xenopus tropicalis	8831	Xenbase:XB-GENE-487270
Danio rerio	9462	ZFIN:ZDB-GENE-070912-180
Drosophila melanogaster	19414	FB:FBgn0004390
Xenopus tropicalis	64926	Xenbase:XB-GENE-6048180
Danio rerio	69601	ZFIN:ZDB-GENE-081104-516
Xenopus tropicalis	240057	Xenbase:XB-GENE-487270
Xenopus tropicalis	853770	Xenbase:XB-GENE-487270