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MIRAGE
malate dehydrogenase MDH1

Summary
Gene Symbol
  • MDH1
Organism
Saccharomyces cerevisiae S288C
NCBI Gene
853777
KEGG Gene ID
sce:YKL085W
PubChem
853777
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Direct protein sequencing
  • Mitochondrion
  • NAD
  • Oxidoreductase
  • Phosphoprotein
  • Reference proteome
  • Transit peptide
  • Tricarboxylic acid cycle
Proteins
Displaying 1 entry
UniProt Protein Name
P17505
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 5 entries
GO Term Evidence Code PMID
tricarboxylic acid cycle
tricarboxylic acid cycle
tricarboxylic acid cycle
malate metabolic process
aerobic respiration
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
malate dehydrogenase
Functional Category
  • C: Energy production and conversion
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 8 entries
Gene Ontology
L-malate dehydrogenase activity
carboxylic acid metabolic process
catalytic activity
malate dehydrogenase activity
malate metabolic process
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity
tricarboxylic acid cycle
Displaying all 7 entries
InterPro
L-lactate/malate dehydrogenase
Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Lactate/malate dehydrogenase, C-terminal
Lactate/malate dehydrogenase, N-terminal
Malate dehydrogenase, active site
Malate dehydrogenase, type 1
NAD(P)-binding domain superfamily
KEGG BRITE Database
Orthology
K00026
Name
malate dehydrogenase [EC:1.1.1.37]
References
Alliance of Genome Resources
Expression
Displaying all 2 entries
Location References
Rhea

RHEA:21432

(S)-malate + NAD+
H+ + oxaloacetate + NADH
Enzyme
PMID
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0080433 developmental and epileptic encephalopathy 51
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025