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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutathione peroxidase GPX1
Summary
- Gene Symbol
-
- GPX1
- Organism
- Saccharomyces cerevisiae S288C
External Links
- NCBI Gene
- 853842
- KEGG Gene ID
- sce:YKL026C
- PubChem
- 853842
- Alliance of Genome Resources
Annotation
- Keyword
-
- Antioxidant
- Disulfide bond
- Mitochondrion outer membrane
- Peroxidase
- Peroxisome
- Redox-active center
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| P36014 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to oxidative stress | ||
| cellular oxidant detoxification | ||
| peroxisome organization | ||
| response to oxidative stress |
| GO Term | Evidence Code | PMID |
|---|---|---|
| peroxisome | ||
| mitochondrial outer membrane | ||
| peroxisomal matrix | ||
| mitochondrion | ||
| cytosol |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| phospholipid-hydroperoxide glutathione peroxidase activity | ||
| peroxidase activity | ||
| glutathione peroxidase activity | ||
| thioredoxin-dependent peroxiredoxin activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Glutathione peroxidase
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- V: Defense mechanisms
| Gene Ontology |
|---|
| cellular oxidant detoxification |
| oxidoreductase activity |
| response to oxidative stress |
| InterPro |
|---|
| Glutathione peroxidase conserved site |
| Glutathione peroxidase |
| Thioredoxin-like superfamily |
KEGG BRITE Database
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050861 | colorectal adenocarcinoma | |
| DOID:0112298 | spondylometaphyseal dysplasia Sedaghatian type | |
| DOID:10591 | pre-eclampsia | |
| DOID:1184 | nephrotic syndrome | |
| DOID:219 | colon cancer | |
| DOID:3021 | acute kidney failure | |
| DOID:3717 | gastric adenocarcinoma | |
| DOID:9256 | colorectal cancer |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP006933
- Gene Name
- glutathione peroxidase GPX1
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 2879 | HGNC:4556 | |||
| 29328 | RGD:69226 | |||
| 37194 | FB:FBgn0034415 | |||
| 67305 | MGI:1914555 | |||
| 69590 | MGI:1916840 | |||
| 184981 | WB:WBGene00009165 | |||
| 187630 | WB:WBGene00011045 | |||
| 188313 | WB:WBGene00020373 | |||
| 352928 | ZFIN:ZDB-GENE-030410-2 | |||
| 352929 | ZFIN:ZDB-GENE-030410-3 |
