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dolichyl-diphosphooligosaccharide--protein glycotransferase OST3

Summary

Gene Symbol

OST3

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

854252

PubChem

854252

Alliance of Genome Resources

SGD:S000005611

Annotation

Keyword

3D-structure
Direct protein sequencing
Disulfide bond
Endoplasmic reticulum
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P48439	Oligosaccharyl transferase 34 kDa subunit Oligosaccharyl transferase subunit OST3 Oligosaccharyl transferase subunit gamma

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein glycosylation	IEA IMP	7622558
protein N-linked glycosylation via asparagine	IBA
protein N-linked glycosylation	IGI IMP IPI	10358084 28598353 9405463
protein O-linked mannosylation	IGI	22492205

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

mannosylation [inference]

protein mannosylation [inference]

protein O-linked mannosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	IEA IMP	7622558
endoplasmic reticulum membrane	IEA
endoplasmic reticulum	HDA IEA	26928762
oligosaccharyltransferase complex	IBA IDA IPI	10358084 9405463

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

oligosaccharyltransferase complex

endoplasmic reticulum protein-containing complex [inference]

oligosaccharyltransferase complex

catalytic complex [inference]

transferase complex [inference]

oligosaccharyltransferase complex

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein-disulfide reductase activity	IDA	23416356
dolichyl-diphosphooligosaccharide-protein glycotransferase activity	IMP	7622558

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors [inference]

disulfide oxidoreductase activity [inference]

protein-disulfide reductase activity

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

oligosaccharyl transferase activity [inference]

dolichyl-diphosphooligosaccharide-protein glycotransferase activity

catalytic activity, acting on a protein [inference]

protein-disulfide reductase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Tumor suppressor candidate 3

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying 1 entry
Gene Ontology
protein N-linked glycosylation via asparagine

Displaying **all 2** entries
InterPro
Oligosaccharyl transferase complex, subunit OST3/OST6
Thioredoxin-like superfamily

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
oligosaccharyltransferase complex	PMID:10358084 PMID:9405463
endoplasmic reticulum	PMID:26928762

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:0080319	X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia	Alliance of Genome Resources
DOID:0081183	autosomal recessive intellectual developmental disorder 7	Alliance of Genome Resources
DOID:0111839	congenital disorder of glycosylation Icc	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:104	bacterial infectious disease	Alliance of Genome Resources
DOID:612	primary immunodeficiency disease	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007406
Gene Name: Ost3p

Ortholog

Displaying entries **1 - 10** of 35 in total

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Species	Gene ID	Alliance of Genome Resources
Homo sapiens	7991	HGNC:30242
Drosophila melanogaster	34137	FB:FBgn0032015
Mus musculus	67075	MGI:1914325
Mus musculus	80286	MGI:1933134
Homo sapiens	84061	HGNC:28880
Rattus norvegicus	116967	RGD:620094
Caenorhabditis elegans	176089	WB:WBGene00022793
Rattus norvegicus	290783	RGD:1303318
Danio rerio	324944	ZFIN:ZDB-GENE-030131-3667
Danio rerio	553582	ZFIN:ZDB-GENE-050522-381

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Tools

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Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements