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glycerol 2-dehydrogenase (NADP(+)) GCY1

Summary

Gene Symbol

GCY1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

854287

PubChem

854287

Alliance of Genome Resources

SGD:S000005646

Annotation

Keyword

Cytoplasm
Glycerol metabolism
NADP
Oxidoreductase
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P14065	Galactose-inducible crystallin-like protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
glycerol to glycerone phosphate metabolic process	IGI IMP	22979944
D-xylose catabolic process	IDA IEA	12271459
cellular response to oxidative stress	IEA IGI	17919749
glycerol metabolic process	IEA
arabinose catabolic process	IDA IEA	12271459

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

glycerol to glycerone phosphate metabolic process

organophosphate metabolic process [inference]

glycerol to glycerone phosphate metabolic process

cellular ketone metabolic process [inference]

glycerol to glycerone phosphate metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

pentose metabolic process [inference]

pentose catabolic process [inference]

arabinose metabolic process [inference]

arabinose catabolic process

D-xylose metabolic process [inference]

D-xylose catabolic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

glycerol to glycerone phosphate metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

pentose metabolic process [inference]

pentose catabolic process [inference]

arabinose metabolic process [inference]

arabinose catabolic process

D-xylose metabolic process [inference]

D-xylose catabolic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

glycerol to glycerone phosphate metabolic process

primary alcohol metabolic process [inference]

glycerol to glycerone phosphate metabolic process

cellular ketone metabolic process [inference]

glycerol to glycerone phosphate metabolic process

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

pentose metabolic process [inference]

pentose catabolic process [inference]

arabinose metabolic process [inference]

arabinose catabolic process

D-xylose metabolic process [inference]

D-xylose catabolic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

glycerol to glycerone phosphate metabolic process

organophosphate metabolic process [inference]

glycerol to glycerone phosphate metabolic process

cellular ketone metabolic process [inference]

glycerol to glycerone phosphate metabolic process

carbohydrate derivative metabolic process [inference]

glycerol to glycerone phosphate metabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

glycerol to glycerone phosphate metabolic process

primary alcohol metabolic process [inference]

glycerol to glycerone phosphate metabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

glycerol to glycerone phosphate metabolic process

organophosphate metabolic process [inference]

glycerol to glycerone phosphate metabolic process

cellular ketone metabolic process [inference]

glycerol to glycerone phosphate metabolic process

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

response to stimulus [inference]

response to stress [inference]

response to oxidative stress [inference]

cellular response to oxidative stress

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	HDA	14562095
cytosol	IBA
cytoplasm	HDA IEA	14562095

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
oxidoreductase activity	IDA IEA	17962934
glycerol dehydrogenase [NAD(P)+] activity	IMP	22979944
alditol:NADP+ 1-oxidoreductase activity	IBA IDA IEA	11306085
mRNA binding	IDA	20844764
glycerol 2-dehydrogenase (NADP+) activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

aldo-keto reductase (NADP) activity

alcohol dehydrogenase (NADP+) activity [inference]

alditol:NADP+ 1-oxidoreductase activity

binding [inference]

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

mRNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

aldo-keto

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
alditol
oxidoreductase activity

Displaying **all 4** entries
InterPro
Aldo-keto reductase
Aldo/keto reductase, conserved site
NADP-dependent oxidoreductase domain superfamily
NADP-dependent oxidoreductase domain

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
nucleus	PMID:14562095
cytoplasm	PMID:14562095

Disease

Disease Ontology

Displaying entries **21 - 23** of 23 in total

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DO ID	Disease Name	Source
DOID:9743	diabetic neuropathy	Alliance of Genome Resources
DOID:9870	galactosemia	Alliance of Genome Resources
DOID:9970	obesity	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 88 in total

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Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	116463	RGD:620257
Mus musculus	116852	MGI:2151104
Caenorhabditis elegans	175047	WB:WBGene00012722
Caenorhabditis elegans	175048	WB:WBGene00012723
Caenorhabditis elegans	178844	WB:WBGene00020369
Rattus norvegicus	192242	RGD:620752
Rattus norvegicus	286921	RGD:708475
Rattus norvegicus	291283	RGD:1311841
Rattus norvegicus	296972	RGD:1308277
Rattus norvegicus	307091	RGD:1309599