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diacylglycerol O-acyltransferase

Summary

Gene Symbol

DGA1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

854419

PubChem

854419

Alliance of Genome Resources

SGD:S000005771

Annotation

Keyword

Acyltransferase
Endoplasmic reticulum
Glycerol metabolism
Glycoprotein
Lipid biosynthesis
Lipid droplet
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q08650	Acyl-CoA-dependent diacylglycerol O-acyltransferase Acyl-CoA:monoacylglycerol acyltransferase Triacylglycerol synthase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
glycerol metabolic process	IEA
lipid metabolic process	IEA
ceramide metabolic process	IDA	22738231
ceramide metabolic process	IMP	22738231
triglyceride biosynthetic process	IDA	11751830

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

lipid metabolic process

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

lipid metabolic process

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

triglyceride biosynthetic process

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular triglyceride homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular triglyceride homeostasis

lipid homeostasis [inference]

acylglycerol homeostasis [inference]

triglyceride homeostasis [inference]

intracellular triglyceride homeostasis

localization [inference]

maintenance of location [inference]

lipid storage

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA
endoplasmic reticulum	HDA	26928762
endoplasmic reticulum membrane	IBA
endoplasmic reticulum membrane	IEA
lipid droplet	IDA	11751830 24868093

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular non-membrane-bounded organelle [inference]

lipid droplet

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
2-acylglycerol O-acyltransferase activity	IEA
diacylglycerol O-acyltransferase activity	IDA	20225889
diacylglycerol O-acyltransferase activity	IMP	11751830
diacylglycerol O-acyltransferase activity	IBA
diacylglycerol O-acyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

O-acyltransferase activity

acylglycerol O-acyltransferase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Acyltransferase

Functional Category

I: Lipid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
O-acyltransferase activity
diacylglycerol O-acyltransferase activity
transferase activity
triglyceride biosynthetic process

Displaying 1 entry
InterPro
Diacylglycerol acyltransferase

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
lipid droplet	PMID:11751830 PMID:24868093
endoplasmic reticulum	PMID:26928762
membrane	PMID:21321129

Ortholog

Displaying entries **1 - 10** of 20 in total

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Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	2181	Xenbase:XB-GENE-5753328
Xenopus tropicalis	67800	Xenbase:XB-GENE-1017054
Xenopus tropicalis	68393	Xenbase:XB-GENE-1004226
Xenopus tropicalis	74205	Xenbase:XB-GENE-5753328
Xenopus tropicalis	80168	Xenbase:XB-GENE-6040330
Xenopus tropicalis	84649	Xenbase:XB-GENE-1017054
Xenopus tropicalis	116255	Xenbase:XB-GENE-1004226
Xenopus tropicalis	233549	Xenbase:XB-GENE-6040330
Xenopus tropicalis	252900	Xenbase:XB-GENE-1017054
Xenopus tropicalis	346606	Xenbase:XB-GENE-959736