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Mlp2p

Summary

Gene Symbol

MLP2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

854657

PubChem

854657

Alliance of Genome Resources

SGD:S000001411

Annotation

Keyword

Coiled coil
Cytoskeleton
Nuclear pore complex
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P40457	Myosin-like protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	IMP	20932479
post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery	IMP	20932479
regulation of transcription, DNA-templated	IGI	15692572
regulation of DNA-templated transcription	IGI	15692572
mRNA export from nucleus	IBA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule organizing center organization [inference]

spindle pole body organization

cell cycle process [inference]

spindle pole body organization

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

cellular response to stimulus [inference]

cellular response to biotic stimulus [inference]

response to cell cycle checkpoint signaling [inference]

response to mitotic cell cycle checkpoint signaling [inference]

response to mitotic spindle checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

response to spindle checkpoint signaling [inference]

response to mitotic spindle checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

response to spindle assembly checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery

post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery

microtubule organizing center organization [inference]

spindle pole body organization

response to stimulus [inference]

response to biotic stimulus [inference]

cellular response to biotic stimulus [inference]

response to cell cycle checkpoint signaling [inference]

response to mitotic cell cycle checkpoint signaling [inference]

response to mitotic spindle checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

response to spindle checkpoint signaling [inference]

response to mitotic spindle checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

response to spindle assembly checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

response to cell cycle checkpoint signaling [inference]

response to mitotic cell cycle checkpoint signaling [inference]

response to mitotic spindle checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

response to spindle checkpoint signaling [inference]

response to mitotic spindle checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

response to spindle assembly checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

cellular response to stimulus [inference]

cellular response to biotic stimulus [inference]

response to cell cycle checkpoint signaling [inference]

response to mitotic cell cycle checkpoint signaling [inference]

response to mitotic spindle checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

response to spindle checkpoint signaling [inference]

response to mitotic spindle checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

response to spindle assembly checkpoint signaling [inference]

response to mitotic cell cycle spindle assembly checkpoint signaling [inference]

negative regulation of protein import into nucleus during spindle assembly checkpoint

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

organic substance transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

mRNA transport

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

nitrogen compound transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

mRNA transport

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

mRNA transport

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

organelle localization [inference]

chromosome localization [inference]

telomere localization [inference]

telomere tethering at nuclear periphery

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
nucleus	IEA
nuclear envelope	IDA	10085285
nuclear envelope	IEA
nuclear pore	IBA
nuclear pore	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

cellular anatomical entity [inference]

microtubule organizing center [inference]

spindle pole body

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

Displaying **all 3** entries
GO Term	Evidence Code	PMID
structural constituent of nuclear pore	IBA
ribonucleoprotein complex binding	IGI	15692572
ribonucleoprotein complex binding	IPI	15692572

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of nuclear pore

binding [inference]

protein-containing complex binding [inference]

ribonucleoprotein complex binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Mlp1

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
mRNA export from nucleus
protein import into nucleus
regulation of mitotic spindle assembly

Displaying 1 entry
InterPro
Nucleoprotein TPR/MLP1

Alliance of Genome Resources

Expression

Displaying **all 5** entries
Location	References
nuclear pore nuclear basket	PMID:24152732
nuclear envelope	PMID:10085285
spindle pole body	PMID:16027220
nucleoplasm	PMID:10085285
mitochondrion	PMID:14576278 PMID:16823961

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1324	lung cancer	Alliance of Genome Resources

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Danio rerio	7175	ZFIN:ZDB-GENE-081104-2
Danio rerio	108989	ZFIN:ZDB-GENE-081104-2
Danio rerio	853970	ZFIN:ZDB-GENE-081104-2
Danio rerio	854657	ZFIN:ZDB-GENE-081104-2

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements