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cytochrome-b5 reductase

Summary

Gene Symbol

CBR1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

854768

KEGG Gene ID

sce:YIL043C

PubChem

854768

Alliance of Genome Resources

SGD:S000001305

Annotation

Keyword

3D-structure
FAD
Mitochondrion outer membrane
NAD
Oxidoreductase
Reference proteome
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P38626	Microsomal cytochrome b reductase P35

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
tRNA wobble uridine modification	IMP	27694803
protein histidyl modification to diphthamide	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-histidine modification [inference]

protein histidyl modification to diphthamide

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-histidine modification [inference]

protein histidyl modification to diphthamide

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-histidine modification [inference]

protein histidyl modification to diphthamide

macromolecule modification [inference]

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-histidine modification [inference]

protein histidyl modification to diphthamide

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-histidine modification [inference]

protein histidyl modification to diphthamide

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	HDA	26928762
plasma membrane	IBA
mitochondrial outer membrane	HDA IEA	16407407
mitochondrion	HDA IEA	14576278 16823961 24769239

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
oxidoreductase activity	IEA
cytochrome-b5 reductase activity, acting on NAD(P)H	IDA IEA	14930 27694803
transferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on NAD(P)H [inference]

oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [inference]

cytochrome-b5 reductase activity, acting on NAD(P)H

transferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00326

Name

cytochrome-b5 reductase [EC:1.6.2.2]

References

10611283

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
mitochondrial outer membrane	PMID:16407407
nucleus	PMID:26928762
mitochondrion	PMID:14576278 PMID:16823961 PMID:24769239

Rhea

NADH

H⁺ + NAD⁺

Enzyme

1.6.2.2

PMID

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0060076	estrogen-receptor negative breast cancer	Alliance of Genome Resources
DOID:10783	methemoglobinemia	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 16 in total

1

2

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	179029	WB:WBGene00020268
Caenorhabditis elegans	188150	WB:WBGene00020267
Drosophila melanogaster	39336	FB:FBgn0036211
Danio rerio	324560	ZFIN:ZDB-GENE-030131-3281
Danio rerio	336553	ZFIN:ZDB-GENE-030131-8497
Danio rerio	751641	ZFIN:ZDB-GENE-060825-83
Xenopus tropicalis	595026	Xenbase:XB-GENE-1006041
Xenopus tropicalis	100488016	Xenbase:XB-GENE-946788
Homo sapiens	1727	HGNC:2873
Homo sapiens	51700	HGNC:24376

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024