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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
8-oxoguanine glycosylase OGG1
Summary
- Gene Symbol
-
- OGG1
- Organism
- Saccharomyces cerevisiae S288C
Annotation
- Keyword
-
- DNA repair
- Glycosidase
- Lyase
- Multifunctional enzyme
- Nucleus
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| P53397 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleotide-excision repair |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
biosynthetic process [inference]
cellular metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| oxidized base lesion DNA N-glycosylase activity | ||
| 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity | ||
| lyase activity | ||
| hydrolase activity, acting on glycosyl bonds | ||
| class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- glycosylase
- Functional Category
-
- E: Amino acid transport and metabolism
- L: Replication, recombination and repair
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity |
| DNA repair |
| base-excision repair, AP site formation |
| base-excision repair |
| catalytic activity |
| damaged DNA binding |
| InterPro |
|---|
| 8-oxoguanine DNA glycosylase, N-terminal |
| DNA glycosylase |
| Helix-hairpin-helix, base-excision DNA repair, C-terminal |
| HhH-GPD domain |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1824 | status epilepticus | |
| DOID:2237 | hepatitis | |
| DOID:224 | transient cerebral ischemia | |
| DOID:2394 | ovarian cancer | |
| DOID:2513 | basal cell carcinoma | |
| DOID:2671 | transitional cell carcinoma | |
| DOID:3314 | angiomyolipoma | |
| DOID:3393 | coronary artery disease | |
| DOID:3525 | middle cerebral artery infarction | |
| DOID:4450 | renal cell carcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11495195 | 1071378_0:0008e4 | |||
| 11502116 | 4950_0:0009f7 | |||
| 11529168 | 1064592_0:000067 | |||
| 11535050 | 1071381_0:00036e | |||
| 13883461 | 1071382_0:001203 | |||
| 14496590 | 1071380_0:000d17 | |||
| 28725399 | 45286_0:000eb8 | |||
| 28933168 | 1080349_0:000f12 | |||
| 34526348 | 1071383_0:000a06 | |||
| 34685096 | 1245769_0:0005b9 |
