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FG-nucleoporin NUP116

Summary

Gene Symbol

NUP116

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

855066

PubChem

855066

Alliance of Genome Resources

SGD:S000004650

Annotation

Keyword

3D-structure
Membrane
Nuclear pore complex
Phosphoprotein
Reference proteome
Repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
Q02630	Nuclear pore protein NUP116/NSP116

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
nuclear pore organization	IMP	9463388
tRNA export from nucleus	IMP	8524308 9802895
protein transport	IEA
mRNA transport	IEA
ribosomal large subunit export from nucleus	IMP	11071906

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

ribosomal subunit export from nucleus [inference]

ribosomal large subunit export from nucleus

RNA export from nucleus

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

nuclear pore organization

chromosome organization [inference]

transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [inference]

post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery

protein-containing complex organization [inference]

nuclear pore organization

localization [inference]

protein-containing complex localization [inference]

ribosomal subunit export from nucleus [inference]

ribosomal large subunit export from nucleus

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

ribosomal subunit export from nucleus [inference]

ribosomal large subunit export from nucleus

RNA export from nucleus

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

organic substance transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

mRNA transport

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

tRNA transport [inference]

tRNA export from nucleus

nitrogen compound transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

mRNA transport

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

tRNA transport [inference]

tRNA export from nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

mRNA transport

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

tRNA transport [inference]

tRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

ribosomal subunit export from nucleus [inference]

ribosomal large subunit export from nucleus

RNA export from nucleus

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

establishment of organelle localization [inference]

ribosomal subunit export from nucleus [inference]

ribosomal large subunit export from nucleus

organelle localization [inference]

ribosome localization [inference]

ribosomal subunit export from nucleus [inference]

ribosomal large subunit export from nucleus

chromosome localization [inference]

telomere localization [inference]

telomere tethering at nuclear periphery

establishment of organelle localization [inference]

ribosomal subunit export from nucleus [inference]

ribosomal large subunit export from nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

ribosomal subunit export from nucleus [inference]

ribosomal large subunit export from nucleus

RNA export from nucleus

mRNA export from nucleus

poly(A)+ mRNA export from nucleus

ncRNA export from nucleus [inference]

tRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nuclear membrane	IEA
membrane	IEA
nuclear pore central transport channel	IDA IEA	18046406
nuclear pore	IDA IEA	10684247 1385442
nuclear envelope

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

nuclear membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nuclear localization sequence binding	IBA
structural constituent of nuclear pore	IBA IEA IGI IMP IPI	11387327 12917401 17418788 17803941 17875746
identical protein binding
RNA binding	IBA
ATPase binding

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of nuclear pore

binding [inference]

protein binding [inference]

enzyme binding [inference]

ATPase binding

identical protein binding

amide binding [inference]

peptide binding [inference]

signal sequence binding [inference]

nuclear localization sequence binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Nuclear pore complex protein

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
RNA export from nucleus
mRNA transport
nuclear localization sequence binding
post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
protein import into nucleus
telomere tethering at nuclear periphery

Displaying **all 4** entries
InterPro
Nuclear pore complex protein NUP96, C-terminal domain
Nuclear pore complex protein Nup98-Nup96-like, autopeptidase S59 domain superfamily
Nuclear pore complex protein Nup98-Nup96-like, autopeptidase S59 domain
Nucleoporin peptidase S59-like

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
nuclear pore central transport channel	PMID:18046406
nuclear pore cytoplasmic filaments	PMID:14960378
nuclear pore	PMID:10684247 PMID:1385442

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:5603	T-cell acute lymphoblastic leukemia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 41 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	4928		HGNC:8068
Drosophila melanogaster	42816		FB:FBgn0039120
Rattus norvegicus	81738		RGD:71033
Caenorhabditis elegans	175852		WB:WBGene00003796
Mus musculus	269966		MGI:109404
Danio rerio	777756		ZFIN:ZDB-GENE-040426-1180
Kluyveromyces lactis	2894863	28985_0:0010f2
Eremothecium gossypii ATCC 10895	4619149	284811_0:000331
Vanderwaltozyma polyspora DSM 70294	5542620	436907_0:00013b
Vanderwaltozyma polyspora DSM 70294	5543839	436907_0:000592