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Annotation

Keyword

3D-structure
Acetylation
Membrane
Mitosis
Nuclear pore complex
Phosphoprotein
Reference proteome
Repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
Q03790	Nuclear pore protein NUP53

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
NLS-bearing protein import into nucleus	IBA IGI IMP	11071914
nuclear pore organization	IBA IGI	19414609
protein transport	IEA
mRNA transport	IEA
protein import into nucleus	IGI	9864357

GO Hierarchy

biological process

cellular process [inference]

cell division

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, centromeric region [inference]

protein localization to kinetochore

protein localization to condensed chromosome [inference]

protein localization to kinetochore

protein localization to nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

cellular response to stimulus [inference]

cellular response to biotic stimulus [inference]

response to cell cycle checkpoint signaling [inference]

response to spindle checkpoint signaling

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

nuclear pore organization

protein-containing complex organization [inference]

nuclear pore organization

response to stimulus [inference]

response to biotic stimulus [inference]

cellular response to biotic stimulus [inference]

response to cell cycle checkpoint signaling [inference]

response to spindle checkpoint signaling

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

response to cell cycle checkpoint signaling [inference]

response to spindle checkpoint signaling

cellular response to stimulus [inference]

cellular response to biotic stimulus [inference]

response to cell cycle checkpoint signaling [inference]

response to spindle checkpoint signaling

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, centromeric region [inference]

protein localization to kinetochore

protein localization to condensed chromosome [inference]

protein localization to kinetochore

protein localization to nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

organic substance transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

nitrogen compound transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

mRNA transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, centromeric region [inference]

protein localization to kinetochore

protein localization to condensed chromosome [inference]

protein localization to kinetochore

protein localization to nucleus [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

NLS-bearing protein import into nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of post-translational protein modification [inference]

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein desumoylation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of post-translational protein modification [inference]

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein desumoylation

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of post-translational protein modification [inference]

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein desumoylation

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of nuclear division [inference]

regulation of mitotic nuclear division

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic nuclear division

regulation of cell cycle process [inference]

regulation of mitotic nuclear division

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nuclear membrane	IEA
membrane	IEA
nuclear pore nuclear basket	IBA IDA	11071914
nuclear pore central transport channel	IBA IDA	18046406
nuclear pore	IDA IEA	10684247 11071914 9864357

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

nuclear membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleic acid binding	IEA
structural constituent of nuclear pore	IBA IEA IPI	17418788 9864357
single-stranded DNA binding	IDA	17897934
identical protein binding
phospholipid binding	IBA IDA	17897934

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of nuclear pore

binding [inference]

protein binding [inference]

identical protein binding

lipid binding [inference]

phospholipid binding

organic cyclic compound binding [inference]

nucleic acid binding

DNA binding [inference]

single-stranded DNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

peptidyl-tRNA hydrolase

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
hydrolase activity
negative regulation of anoikis
positive regulation of anoikis

Displaying **all 2** entries
InterPro
Peptidyl-tRNA hydrolase II domain superfamily
Peptidyl-tRNA hydrolase, PTH2

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
nuclear pore	PMID:10684247 PMID:11071914 PMID:9864357
nuclear pore central transport channel	PMID:18046406
nuclear pore nuclear basket	PMID:11071914

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080072	intestinal pseudo-obstruction	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 34 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Drosophila melanogaster	32851		FB:FBgn0030943
Mus musculus	69482		MGI:1916732
Homo sapiens	129401		HGNC:29797
Caenorhabditis elegans	174663		WB:WBGene00003805
Rattus norvegicus	295692		RGD:1303069
Danio rerio	337461		ZFIN:ZDB-GENE-030131-9407
Xenopus tropicalis	493486		Xenbase:XB-GENE-980941
Kluyveromyces lactis	2895975	28985_0:000f6d
Eremothecium gossypii ATCC 10895	4620530	284811_0:000546
Vanderwaltozyma polyspora DSM 70294	5546072	436907_0:000df8

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements