GlyCosmos Portal

Submissions

glutamate decarboxylase GAD1

Summary

Gene Symbol

GAD1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

855291

KEGG Gene ID

sce:YMR250W

PubChem

855291

Alliance of Genome Resources

SGD:S000004862

Annotation

Keyword

Decarboxylase
Pyridoxal phosphate
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q04792

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cellular response to oxidative stress	IMP	11031268
glutamate catabolic process	IBA IMP	11031268
glutamate metabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid metabolic process [inference]

glutamate metabolic process

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

response to stimulus [inference]

response to stress [inference]

response to oxidative stress [inference]

cellular response to oxidative stress

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IBA
cytoplasm	HDA	11914276 14562095

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
glutamate decarboxylase activity	IBA IEA IMP	11031268
carboxy-lyase activity	IEA
pyridoxal phosphate binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

carboxy-lyase activity

glutamate decarboxylase activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

organic cyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01580

Name

glutamate decarboxylase [EC:4.1.1.15]

References

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
cytoplasm	PMID:11914276 PMID:14562095

Rhea

RHEA:17785

H⁺ + L-glutamate

CO₂ + 4-aminobutanoate

Enzyme

4.1.1.15

PMID

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements