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dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase

Summary

Gene Symbol

ALG9

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

855502

KEGG Gene ID

sce:YNL219C

PubChem

855502

Alliance of Genome Resources

SGD:S000005163

Annotation

Keyword

Endoplasmic reticulum
Glycosyltransferase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P53868	Asparagine-linked glycosylation protein 9 Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein modification process	IEA
protein glycosylation	IEA IMP	8692962
protein N-linked glycosylation	IBA IDA	15987956
carbohydrate derivative biosynthetic process	IEA
dolichol-linked oligosaccharide biosynthetic process	IMP	15987956

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

protein glycosylation

protein N-linked glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

protein metabolic process [inference]

protein modification process

protein glycosylation

protein N-linked glycosylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process

protein glycosylation

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process

protein glycosylation

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

protein glycosylation

protein N-linked glycosylation

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IEA
endoplasmic reticulum membrane	IBA IEA
endoplasmic reticulum	HDA IEA IMP	26928762 8692962

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 5** entries
GO Term	Evidence Code	PMID
alpha-1,2-mannosyltransferase activity	IBA
dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	IDA IEA	15987956
dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	IDA IEA	15987956
mannosyltransferase activity	IEA IMP	8692962
glycosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

hexosyltransferase activity [inference]

mannosyltransferase activity

alpha-1,2-mannosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Mannosyltransferase

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
alpha-1,2-mannosyltransferase activity
dol-P-Man
dol-P-Man
protein N-linked glycosylation
transferase activity

Displaying 1 entry
InterPro
GPI mannosyltransferase

KEGG BRITE Database

Orthology

K03846

Name

alpha-1,2-mannosyltransferase [EC:2.4.1.259 2.4.1.261]

References

15148656

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R06261	2.4.1.261	G48148JS G74840NI	G39578OU
R06259	2.4.1.259	G44865OQ G74840NI	G72103RY

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
endoplasmic reticulum	PMID:26928762

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050570	congenital disorder of glycosylation type I	Alliance of Genome Resources
DOID:0080564	congenital disorder of glycosylation Il	Alliance of Genome Resources
DOID:3312	bipolar disorder	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP007032
Gene Name: dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase

Ortholog

Displaying entries **1 - 10** of 29 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Drosophila melanogaster	43031		FB:FBgn0039293
Homo sapiens	79796		HGNC:15672
Mus musculus	102580		MGI:1924753
Caenorhabditis elegans	174633		WB:WBGene00007556
Rattus norvegicus	367083		RGD:1311272
Danio rerio	393598		ZFIN:ZDB-GENE-040426-1270
Kluyveromyces lactis	2893506	28985_0:000906
Eremothecium gossypii ATCC 10895	4618842	284811_0:0001e3
Vanderwaltozyma polyspora DSM 70294	5544341	436907_0:000776
Lachancea thermotolerans CBS 6340	8290980	559295_0:0001eb

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements