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citrate (Si)-synthase CIT3

Summary

Gene Symbol

CIT3

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

856107

PubChem

856107

Alliance of Genome Resources

SGD:S000006205

Annotation

Keyword

Mitochondrion
Reference proteome
Transferase
Transit peptide
Tricarboxylic acid cycle

Proteins

Displaying 1 entry
UniProt	Protein Name
P43635

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IBA
propionate catabolic process, 2-methylcitrate cycle	IGI	17570335
tricarboxylic acid cycle	IBA IDA IEA	17570335

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

propionate metabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

organic substance metabolic process [inference]

carbohydrate metabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid metabolic process [inference]

propionate metabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

short-chain fatty acid catabolic process [inference]

propionate catabolic process [inference]

propionate catabolic process, 2-methylcitrate cycle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrial matrix	IBA
mitochondrion	HDA IDA IEA	16823961 24769239 9140965

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 5** entries
GO Term	Evidence Code	PMID
2-methylcitrate synthase activity	IBA IDA IMP	17570335
citrate synthase activity	IEA
transferase activity	IEA
citrate (Si)-synthase activity	IBA IDA IEA IMP	17570335
acyltransferase activity, acyl groups converted into alkyl on transfer	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

acyltransferase activity [inference]

acyltransferase activity, acyl groups converted into alkyl on transfer

citrate synthase activity

citrate (Si)-synthase activity

2-methylcitrate synthase activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
mitochondrion	PMID:16823961 PMID:24769239 PMID:9140965

Disease

Disease Ontology

Displaying **all 9** entries
DO ID	Disease Name	Source
DOID:0050852	limb ischemia	Alliance of Genome Resources
DOID:11984	hypertrophic cardiomyopathy	Alliance of Genome Resources
DOID:12930	dilated cardiomyopathy	Alliance of Genome Resources
DOID:1459	hypothyroidism	Alliance of Genome Resources
DOID:3312	bipolar disorder	Alliance of Genome Resources
DOID:5844	myocardial infarction	Alliance of Genome Resources
DOID:6000	congestive heart failure	Alliance of Genome Resources
DOID:7998	hyperthyroidism	Alliance of Genome Resources
DOID:8466	retinal degeneration	Alliance of Genome Resources

Ortholog

Displaying **all 9** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	176437	WB:WBGene00000833
Drosophila melanogaster	31579	FB:FBgn0261955
Drosophila melanogaster	41468	FB:FBgn0037988
Danio rerio	322339	ZFIN:ZDB-GENE-030131-1058
Xenopus tropicalis	550067	Xenbase:XB-GENE-943160
Homo sapiens	1431	HGNC:2422
Mus musculus	12974	MGI:88529
Mus musculus	71832	MGI:1919082
Rattus norvegicus	170587	RGD:620330

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.0.0

Last updated: August 19, 2024