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gamma-secretase subunit Aph-1

Summary

Gene Symbol

aph1

Organism

Dictyostelium discoideum AX4

External Links

NCBI Gene: 8616267
PubChem: 8616267

Annotation

Keyword

Glycoprotein
Notch signaling pathway
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q55FS3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

1

2

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GO Term	Evidence Code	PMID
phagocytosis	IMP	30806144
phagocytosis	IGI	20699477
autophagy	IMP	30806144
Notch signaling pathway	IEA
protein processing	IMP	20699477

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

catabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

vesicle-mediated transport [inference]

endocytosis [inference]

pinocytosis [inference]

macropinocytosis

phagocytosis

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular developmental process [inference]

cell differentiation [inference]

sorocarp spore cell differentiation

process utilizing autophagic mechanism [inference]

autophagy

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

sorocarp spore cell differentiation

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

pinocytosis [inference]

macropinocytosis

phagocytosis

import into cell [inference]

endocytosis [inference]

pinocytosis [inference]

macropinocytosis

phagocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity

Displaying **all 5** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA	30806144
endoplasmic reticulum	IBA
membrane	IEA
gamma-secretase complex	IMP	20699477
gamma-secretase complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

gamma-secretase complex

catalytic complex [inference]

gamma-secretase complex

cellular anatomical entity [inference]

membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying 1 entry
GO Term	Evidence Code	PMID
protein-macromolecule adaptor activity	IBA

GO Hierarchy

molecular function

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

APH-1

Functional Category

J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
Notch receptor processing
protein-macromolecule adaptor activity

Displaying 1 entry
InterPro
Gamma-secretase subunit Aph-1

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements