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eukaryotic translation initiation factor 3 subunit G

Summary

Gene Symbol

EIF3G

Organism

Homo sapiens (human)

External Links

NCBI Gene

8666

PubChem

8666

Alliance of Genome Resources

HGNC:3274

JoGo

EIF3G

TogoVar

EIF3G

Annotation

Keyword

3D-structure
Cytoplasm
Direct protein sequencing
Initiation factor
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
O75821	Eukaryotic translation initiation factor 3 RNA-binding subunit Eukaryotic translation initiation factor 3 subunit 4 eIF-3-delta eIF3 p42 eIF3 p44

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
formation of cytoplasmic translation initiation complex	NAS	16920360
translational initiation	IC	17322308 18599441
translational initiation	IDA	17581632
viral translational termination-reinitiation	IDA	21347434

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

translational initiation

cellular process [inference]

cellular metabolic process [inference]

translational initiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

formation of cytoplasmic translation initiation complex

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

formation of cytoplasmic translation initiation complex

protein-RNA complex organization [inference]

protein-RNA complex assembly [inference]

formation of cytoplasmic translation initiation complex

viral process [inference]

viral translational termination-reinitiation

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nucleus	IDA	12426392
cytoplasm	IDA	12426392
cytosol	TAS
cytosol	IDA
eukaryotic translation initiation factor 3 complex	IDA	17322308 17581632 18599441 25849773

GO Hierarchy

cellular component

protein-containing complex [inference]

eukaryotic translation initiation factor 3 complex

ribonucleoprotein complex [inference]

translation preinitiation complex [inference]

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

perinuclear region of cytoplasm

Displaying **all 5** entries
GO Term	Evidence Code	PMID
RNA binding	IDA	25849773 27462815
RNA binding	HDA	22658674 22681889
translation initiation factor activity	IC	17322308 18599441
translation initiation factor activity	IDA	17581632 25849773
protein binding	IPI	14688252 17094969 18599441 18628297 20406461 21044950 23804756 24396066 25416956 25959826 26100019 28514442 30021884 32296183 32814053 33961781 35271311 36950384 39251607

GO Hierarchy

molecular function

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding [inference]

translation initiation factor activity

translation regulator activity [inference]

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding [inference]

translation initiation factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

eukaryotic translation initiation factor 3 subunit

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cytoplasmic translational initiation
formation of cytoplasmic translation initiation complex

Displaying **all 6** entries
InterPro
Eukaryotic translation initiation factor 3 subunit G, N-terminal
Eukaryotic translation initiation factor 3 subunit G
Nucleotide-binding alpha-beta plait domain superfamily
RNA recognition motif domain
RNA-binding domain superfamily
eIF3G, RNA recognition motif