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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
solute carrier family 4 member 4
Summary
- Gene Symbol
-
- SLC4A4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Retinitis pigmentosa
- Sodium transport
- Symport
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| monoatomic anion transmembrane transport |
GO Hierarchy
biological process
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| plasma membrane | ||
| cell surface | ||
| basolateral plasma membrane | ||
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| symporter activity | ||
| monoatomic anion transmembrane transporter activity | ||
| sodium:bicarbonate symporter activity | ||
| identical protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Sodium bicarbonate cotransporter
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| inorganic anion transport |
| solute |
| InterPro |
|---|
| Bicarbonate transporter, eukaryotic |
| Bicarbonate transporter-like, transmembrane domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10763 | hypertension | |
| DOID:12387 | nephrogenic diabetes insipidus | |
| DOID:14219 | renal tubular acidosis | |
| DOID:2355 | anemia | |
| DOID:4947 | cholangiocarcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 568631 | ZFIN:ZDB-GENE-060526-274 | DANRE36782 | ||
| 705830 | MACMU35994 | |||
| 855446 | SGD:S000005219 | |||
| 100008727 | RABIT05341 | |||
| 100014567 | MONDO25731 | |||
| 100078786 | ORNAN01087 | |||
| 100135635 | CAVPO16783 | |||
| 100217496 | TAEGU23842 | |||
| 100394336 | CALJA28006 | |||
| 100461591 | 9601_0:001643 | PONAB28448 |
