receptor interacting serine/threonine kinase 1

Summary
Gene Symbol
  • RIPK1
Organism
Homo sapiens (human)
NCBI Gene
8737
PubChem
8737
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Alternative splicing
  • Apoptosis
  • Cell membrane
  • Cytoplasm
  • Disease variant
  • Glycoprotein
  • Host-virus interaction
  • Inflammatory response
  • Isopeptide bond
  • Necrosis
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Serine/threonine-protein kinase
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
Q13546
  • Cell death protein RIP
  • Receptor-interacting protein 1
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
serine/threonine-protein kinase
Functional Category
  • K: Transcription
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0111952 immunodeficiency 57
Ortholog
Displaying 1 entry
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
8737 Xenbase:XB-GENE-1012365

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025