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GDP-mannose 4,6-dehydratase

Summary

Gene Symbol

Organism

Pseudomonas aeruginosa PAO1

External Links

NCBI Gene: 883089
PubChem: 883089

Annotation

Keyword

3D-structure
Lipopolysaccharide biosynthesis
Lyase
NADP
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q51366	GDP-D-mannose dehydratase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
lipopolysaccharide biosynthetic process	IMP	8548534
O antigen biosynthetic process	IDA	19459932
GDP-D-rhamnose biosynthetic process	EXP	19459932
GDP-mannose metabolic process
'de novo' GDP-L-fucose biosynthetic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-mannose metabolic process

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-mannose metabolic process

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

phosphorus metabolic process [inference]

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-mannose metabolic process

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-mannose metabolic process

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

O antigen metabolic process [inference]

O antigen biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-mannose metabolic process

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

liposaccharide metabolic process [inference]

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-mannose metabolic process

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

O antigen metabolic process [inference]

O antigen biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

liposaccharide metabolic process [inference]

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

O antigen metabolic process [inference]

O antigen biosynthetic process

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

carbohydrate derivative metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-mannose metabolic process

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

liposaccharide metabolic process [inference]

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-mannose metabolic process

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-mannose metabolic process

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

phosphorus metabolic process [inference]

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-mannose metabolic process

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-mannose metabolic process

GDP-L-fucose metabolic process [inference]

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

GDP-D-rhamnose metabolic process [inference]

GDP-D-rhamnose biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-D-rhamnose biosynthetic process

GDP-L-fucose biosynthetic process [inference]

'de novo' GDP-L-fucose biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
GDP-mannose 4,6-dehydratase activity	EXP	9781879
NADP+ binding

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

GDP-mannose 4,6-dehydratase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding [inference]

NADP+ binding

ion binding [inference]

anion binding [inference]

NADP+ binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding [inference]

NADP+ binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Bacteria

Group Name

dehydrogenase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
GDP-mannose 4,6-dehydratase activity
GDP-mannose metabolic process
NADP+ binding
lyase activity

Displaying **all 3** entries
InterPro
GDP-mannose 4,6-dehydratase
NAD(P)-binding domain superfamily
NAD(P)-binding domain

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements