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MIRAGE

D-alpha-D-heptose-7-phosphate kinase HddA

Summary

Gene Symbol

hddA

Organism

Mycobacterium tuberculosis H37Rv

External Links

NCBI Gene: 886902
PubChem: 886902

Annotation

Keyword

ATP-binding
Carbohydrate metabolism
Kinase
Lipopolysaccharide biosynthesis
Magnesium
Metal-binding
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
O53637	D-alpha-D-heptose 7-phosphate kinase MtbHddA

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
galactose metabolic process
lipopolysaccharide biosynthetic process

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

liposaccharide metabolic process [inference]

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

liposaccharide metabolic process [inference]

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

liposaccharide metabolic process [inference]

lipopolysaccharide metabolic process [inference]

lipopolysaccharide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

lipopolysaccharide biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

lipopolysaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

lipopolysaccharide biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
galactokinase activity
ATP binding
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

carbohydrate kinase activity [inference]

galactokinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

galactokinase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Bacteria

Group Name

kinase

Functional Category

E: Amino acid transport and metabolism
K: Transcription
M: Cell wall/membrane/envelope biogenesis

Displaying **all 6** entries
Gene Ontology
ATP binding
GDP-L-fucose salvage
fucokinase activity
kinase activity
nucleotide binding
phosphorylation

Displaying **all 6** entries
InterPro
D,D-heptose 7-phosphate kinase
GHMP kinase N-terminal domain
GHMP kinase, C-terminal domain superfamily
GHMP kinase, C-terminal domain
Galactokinase/homoserine kinase
Ribosomal protein uS5 domain 2-type superfamily

Rhea

ATP + D-glycero-α-D-manno-heptose 7-phosphate

H⁺ + ADP + D-glycero-α-D-manno-heptose 1,7-bisphosphate

Enzyme

2.7.1.168

PMID

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025