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sphingosine kinase 1

Summary

Gene Symbol

SPHK1

Aliases

SPHK

Organism

Homo sapiens (human)

External Links

NCBI Gene

8877

HGNC

11240

KEGG Gene ID

hsa:8877

PubChem

8877

Alliance of Genome Resources

HGNC:11240

JoGo

SPHK1

TogoVar

SPHK1

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Calmodulin-binding
Cell membrane
Coated pit
Cytoplasm
Endosome
Kinase
Lipid metabolism
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Synapse

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9NYA1	Acetyltransferase SPHK1
Q53ZR5	Acetyltransferase SPHK1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 45 in total

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GO Term	Evidence Code	PMID
blood vessel development	IEA
sphingosine-1-phosphate receptor signaling pathway	IEA
protein acetylation	ISS
sphingosine metabolic process	IDA	20577214
inflammatory response	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

sphingosine biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingolipid catabolic process [inference]

sphingoid catabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein acylation [inference]

protein acetylation

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

macromolecule biosynthetic process [inference]

DNA biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

sphingosine biosynthetic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingolipid catabolic process [inference]

sphingoid catabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingolipid catabolic process [inference]

sphingoid catabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein acylation [inference]

protein acetylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

sphingosine metabolic process

sphingosine biosynthetic process

diol biosynthetic process [inference]

sphingosine biosynthetic process

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingolipid catabolic process [inference]

sphingoid catabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein acylation [inference]

protein acetylation

macromolecule modification [inference]

protein modification process [inference]

protein acylation [inference]

protein acetylation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingolipid catabolic process [inference]

sphingoid catabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein acylation [inference]

protein acetylation

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

macromolecule biosynthetic process [inference]

DNA biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

sphingosine metabolic process

sphingosine biosynthetic process

diol biosynthetic process [inference]

sphingosine biosynthetic process

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

intracellular signal transduction

second-messenger-mediated signaling [inference]

calcium-mediated signaling

sphingolipid mediated signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

cell population proliferation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

sphingosine biosynthetic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingolipid catabolic process [inference]

sphingoid catabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingoid catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

developmental process [inference]

anatomical structure development [inference]

blood vessel development

animal organ development [inference]

brain development

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to oxidative stress [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus

cellular response to vascular endothelial growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus

cellular response to vascular endothelial growth factor stimulus

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to tumor necrosis factor

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

response to inorganic substance [inference]

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to oxygen-containing compound [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte activation [inference]

regulation of macrophage activation [inference]

regulation of microglial cell activation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

regulation of peptidyl-threonine phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of amide metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

regulation of peptidyl-threonine phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of post-translational protein modification [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination [inference]

positive regulation of protein ubiquitination

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

regulation of peptidyl-threonine phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of post-translational protein modification [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination [inference]

positive regulation of protein ubiquitination

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

regulation of peptidyl-threonine phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of post-translational protein modification [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination [inference]

positive regulation of protein ubiquitination

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of p38MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of p38MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

regulation of localization [inference]

regulation of transport [inference]

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

regulation of phagocytosis

regulation of vesicle fusion [inference]

regulation of endosomal vesicle fusion

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth

positive regulation of growth [inference]

positive regulation of cell growth

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cell growth

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of muscle contraction [inference]

positive regulation of smooth muscle contraction

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of p38MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of p38MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

regulation of response to external stimulus [inference]

regulation of inflammatory response [inference]

regulation of neuroinflammatory response

regulation of microglial cell activation

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response [inference]

regulation of neuroinflammatory response

regulation of microglial cell activation

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of p38MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

intracellular signal transduction

second-messenger-mediated signaling [inference]

calcium-mediated signaling

sphingolipid mediated signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of p38MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of p38MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

regulation of peptidyl-threonine phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

regulation of fibroblast proliferation [inference]

positive regulation of fibroblast proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular component biogenesis [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cell growth

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-threonine phosphorylation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of macrophage activation [inference]

regulation of microglial cell activation

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth

regulation of endocytosis

regulation of phagocytosis

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division

regulation of vesicle fusion [inference]

regulation of endosomal vesicle fusion

regulation of nuclear division [inference]

regulation of mitotic nuclear division [inference]

positive regulation of mitotic nuclear division

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic nuclear division [inference]

positive regulation of mitotic nuclear division

positive regulation of mitotic cell cycle

regulation of cell cycle process [inference]

regulation of mitotic nuclear division [inference]

positive regulation of mitotic nuclear division

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

regulation of phagocytosis

regulation of vesicle fusion [inference]

regulation of endosomal vesicle fusion

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of p38MAPK cascade [inference]

positive regulation of p38MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade [inference]

positive regulation of p38MAPK cascade

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of smooth muscle contraction [inference]

positive regulation of smooth muscle contraction

positive regulation of muscle contraction [inference]

positive regulation of smooth muscle contraction

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of macrophage activation [inference]

regulation of microglial cell activation

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-17 production

positive regulation of muscle contraction [inference]

positive regulation of smooth muscle contraction

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleoplasm	TAS
cytoplasm	IDA	15623571 19854831 21075214
cytoplasm	IBA
cytosol	TAS	10863092

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

early endosome membrane

plasma membrane region [inference]

clathrin-coated pit

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

intracellular membrane-bounded organelle

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

presynapse

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
magnesium ion binding	IDA	10947957
lipid kinase activity	TAS
DNA binding	IDA	12393916
protein binding	IPI	12080051 16888242 17064696 17124500 18263879 19854831 20838377 32814053
calmodulin binding	IDA	10947957 12393916