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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sphingosine-1-phosphate lyase 1
Summary
- Gene Symbol
-
- SGPL1
- Aliases
-
- SPL
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Apoptosis
- Disease variant
- Endoplasmic reticulum
- Lyase
- Nitration
- Phosphoprotein
- Proteomics identification
- Pyridoxal phosphate
- Reference proteome
- Signal-anchor
- Sphingolipid metabolism
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O95470 |
|
| A0A8V8TN35 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| fatty acid metabolic process | ||
| luteinization | ||
| face morphogenesis | ||
| spermatogenesis | ||
| skeletal system morphogenesis |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum | ||
| endoplasmic reticulum membrane |
GO Hierarchy
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0050569 | Seckel syndrome | |
| DOID:0050602 | triple-A syndrome | |
| DOID:0050885 | IMAGe syndrome | |
| DOID:0060180 | colitis | |
| DOID:0060189 | ileitis | |
| DOID:0060190 | ileocolitis | |
| DOID:0060254 | Robinow syndrome | |
| DOID:0060260 | ptosis | |
| DOID:0060261 | congenital ptosis |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000028 | Cryptorchidism |
| HP:0000054 | Micropenis |
| HP:0000093 | Proteinuria |
| HP:0000097 | Focal segmental glomerulosclerosis |
| HP:0000100 | Nephrotic syndrome |
| HP:0000135 | Hypogonadism |
| HP:0000252 | Microcephaly |
| HP:0000407 | Sensorineural hearing impairment |
| HP:0000486 | Strabismus |
| Disease ID | Disease Name |
|---|---|
| OMIM:617575 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP000574
- Gene Name
- sphingosine-1-phosphate lyase 1
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 176857 | WB:WBGene00004981 | ||
| 181859 | WB:WBGene00006418 | ||
| 190868 | WB:WBGene00022427 | ||
| 46059 | FB:FBgn0010591 | ||
| 103181428 | CALMI02340 | ||
| 102363827 | LATCH16717 | ||
| 100037312 | ZFIN:ZDB-GENE-070410-24 | DANRE06128 | |
| 103028047 | ASTMX07615 | ||
| 113585228 | ELEEL34606 | ||
| 115153009 | SALTR06906 |
