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Guidelines

MIRAGE

Tax1 binding protein 1

Summary

Gene Symbol

TAX1BP1

Organism

Homo sapiens (human)

External Links

NCBI Gene

8887

KEGG Gene ID

PubChem

8887

Alliance of Genome Resources

HGNC:11575

Annotation

Keyword

3D-structure
Alternative splicing
Apoptosis
Autophagy
Coiled coil
Cytoplasm
Cytoplasmic vesicle
Host-virus interaction
Innate immunity
Mitochondrion
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B4DSG5
Q86VP1	TRAF6-binding protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
autophagy
apoptotic process
negative regulation of tumor necrosis factor-mediated signaling pathway	IDA
negative regulation of tumor necrosis factor-mediated signaling pathway	IEA
negative regulation of toll-like receptor 4 signaling pathway	IDA

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

autophagy

cell death [inference]

programmed cell death [inference]

apoptotic process

process utilizing autophagic mechanism [inference]

autophagy

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to organelle [inference]

protein localization to phagocytic vesicle

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

regulation of immune response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

negative regulation of interleukin-1-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of intracellular signal transduction [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

negative regulation of interleukin-1-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of intracellular signal transduction [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

regulation of response to external stimulus [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

regulation of immune response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

negative regulation of interleukin-1-mediated signaling pathway

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

negative regulation of interleukin-1-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of intracellular signal transduction [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of intracellular signal transduction [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
phagophore assembly site	EXP
phagophore assembly site	IEA
cytoplasm	EXP
cytoplasm	IDA
cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

mitochondrion

vacuole [inference]

autophagosome

intracellular vesicle [inference]

cytoplasmic vesicle

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

vacuole [inference]

autophagosome

intracellular vesicle [inference]

cytoplasmic vesicle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
zinc ion binding
kinase binding	ISS
kinase binding	IEA
protein-macromolecule adaptor activity	IDA

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

signaling adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026