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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-X3-C motif chemokine ligand 1
Summary
- Gene Symbol
-
- Cx3cl1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell adhesion
- Cell membrane
- Chemotaxis
- Cytokine
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to tumor necrosis factor | ||
| neuron cellular homeostasis |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
negative regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of transmembrane transport [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| postsynapse | ||
| neuronal cell body | ||
| plasma membrane | ||
| cell projection |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| integrin binding | ||
| CX3C chemokine receptor binding | ||
| chemokine activity | ||
| CCR chemokine receptor binding | ||
| CXCR1 chemokine receptor binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Transcription initiation factor IIA, gamma subunit, C-terminal
- Functional Category
-
- K: Transcription
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell chemotaxis |
| chemokine activity |
| cytokine activity |
| eosinophil chemotaxis |
| immune response |
| InterPro |
|---|
| Chemokine beta/gamma/delta |
| Chemokine interleukin-8-like domain |
| Chemokine interleukin-8-like superfamily |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2841 | asthma | |
| DOID:2913 | acute pancreatitis | |
| DOID:2921 | glomerulonephritis | |
| DOID:326 | ischemia | |
| DOID:3310 | atopic dermatitis | |
| DOID:418 | systemic scleroderma | |
| DOID:4483 | rhinitis | |
| DOID:4780 | anti-basement membrane glomerulonephritis | |
| DOID:5154 | borna disease | |
| DOID:6432 | pulmonary hypertension |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 127672008 | 10129_0:004f89 | |||
| 128103530 | 564181_0:005126 | |||
| 129687199 | 48139_1:0031bc | |||
| 130863816 | 269649_0:004892 | |||
| 131910822 | 42410_0:001dc5 |
