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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-X3-C motif chemokine ligand 1
Summary
- Gene Symbol
-
- Cx3cl1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell adhesion
- Cell membrane
- Chemotaxis
- Cytokine
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell adhesion | ||
| autocrine signaling | ||
| positive regulation of macrophage chemotaxis | ||
| positive chemotaxis | ||
| inflammatory response |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
negative regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of transmembrane transport [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| neuron projection | ||
| cell surface | ||
| cell body | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| integrin binding | ||
| CX3C chemokine receptor binding | ||
| chemokine activity | ||
| CCR chemokine receptor binding | ||
| CXCR1 chemokine receptor binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Transcription initiation factor IIA, gamma subunit, C-terminal
- Functional Category
-
- K: Transcription
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell chemotaxis |
| chemokine activity |
| cytokine activity |
| eosinophil chemotaxis |
| immune response |
| InterPro |
|---|
| Chemokine beta/gamma/delta |
| Chemokine interleukin-8-like domain |
| Chemokine interleukin-8-like superfamily |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080745 | polymyositis | |
| DOID:0080855 | Parkinsonism | |
| DOID:10223 | dermatomyositis | |
| DOID:10459 | common cold | |
| DOID:10762 | portal hypertension | |
| DOID:13141 | uveitis | |
| DOID:1679 | cystitis | |
| DOID:1824 | status epilepticus | |
| DOID:224 | transient cerebral ischemia | |
| DOID:2527 | nephrosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100470482 | AILME19790 | |||
| 100582586 | NOMLE25483 | |||
| 100621027 | PIGXX27235 | |||
| 100677201 | LOXAF08143 | |||
| 100723932 | 10141_0:002e06 | CAVPO10803 | ||
| 100760591 | 10029_0:0025ec | |||
| 100922003 | SARHA18212 | |||
| 100945057 | OTOGA09740 | |||
| 100979411 | PANPA15276 | |||
| 101004203 | PAPAN16189 |
