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Standards Ontologies Notations
phospholipase C zeta 1

Summary
Gene Symbol
  • PLCZ1
Aliases
  • NYD-SP27
  • PLCzeta
Organism
Homo sapiens (human)
External Links
NCBI Gene
89869
HGNC
19218
KEGG Gene ID
hsa:89869
PubChem
89869
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Calcium
  • Cytoplasm
  • Developmental protein
  • Disease variant
  • Fertilization
  • Hydrolase
  • Lipid degradation
  • Nucleus
  • Reference proteome
  • Transducer
Proteins
Displaying all 2 entries
UniProt Protein Name
A0A140VJR9
Q86YW0
  • Phosphoinositide phospholipase C-zeta-1
  • Phospholipase C-zeta-1
  • Testis-development protein NYD-SP27
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entry 6 - 6 of 6 in total
GO Term Evidence Code PMID
lipid catabolic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
KEGG BRITE Database
Orthology
K05861
Name
phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
References
Rhea

RHEA:33179

H2O + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)
H+ + a 1,2-diacyl-sn-glycerol + 1D-myo-inositol 1,4,5-trisphosphate
Enzyme
PMID
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:0070174 spermatogenic failure 17
DOID:1485 cystic fibrosis
DOID:2394 ovarian cancer
DOID:4001 ovarian carcinoma
DOID:5223 infertility
The Human Phenotype Ontology
Displaying all 3 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0003251 Male infertility
HP:0011462 Young adult onset
Displaying 1 entry
Disease ID Disease Name
OMIM:617214
  • spermatogenic failure 17
PubChem Disease
MedGen Diseases
OMIM Phenotypes
KEGG Diseases
Gene-Disease-Co-Occurrences-in-Literature (PubChem)
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP001791
Gene Name
phospholipase C, zeta 1
Ortholog
Displaying entries 1 - 10 of 54 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
177525 WB:WBGene00004039
102688374 LEPOC16320
105028902 ESOLU57482
100699197 ORENI67668
115586176 SPAAU44808
101931350 CHRPI22855
113437895 PSETE00473
101801909 ANAPP04151
103167538 ORNAN14956
100406733 CALJA44116
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024