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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
phospholipase C zeta 1
Summary
- Gene Symbol
-
- PLCZ1
- Aliases
-
- NYD-SP27
- PLCzeta
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Calcium
- Cytoplasm
- Developmental protein
- Disease variant
- Fertilization
- Hydrolase
- Lipid degradation
- Nucleus
- Reference proteome
- Transducer
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A140VJR9 |
|
| Q86YW0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| lipid catabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| cytosol |
|
|
| pronucleus | ||
| sperm head | ||
| perinuclear region of cytoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| phosphatidylinositol-5-phosphate binding | ||
| phosphatidylinositol-3-phosphate binding | ||
| phosphatidylinositol-4,5-bisphosphate binding | ||
| calcium ion binding | ||
| phosphatidylinositol phospholipase C activity |
GO Hierarchy
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0003251 | Male infertility |
| HP:0011462 | Young adult onset |
| Disease ID | Disease Name |
|---|---|
| OMIM:617214 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP001791
- Gene Name
- phospholipase C, zeta 1
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 855860 | SGD:S000006189 | ||
| 103733964 | NANGA20488 | ||
| 116442523 | CORMO20479 | ||
| 115605170 | STRHB22211 |
