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cytosolic thiouridylase subunit 1

Summary

Gene Symbol

CTU1

Organism

Homo sapiens (human)

External Links

NCBI Gene

90353

PubChem

90353

Alliance of Genome Resources

HGNC:29590

JoGo

CTU1

TogoVar

CTU1

Annotation

Keyword

Cytoplasm
Phosphoprotein
Proteomics identification
Reference proteome
Transferase
tRNA processing
tRNA-binding

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7Z7A3	ATP-binding domain-containing protein 3 Cancer-associated gene protein Cytoplasmic tRNA adenylyltransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
tRNA wobble uridine modification	NAS	19017811
tRNA wobble position uridine thiolation	IBA
protein urmylation	IEA
tRNA thio-modification	NAS	19017811

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein urmylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein urmylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein urmylation

macromolecule modification [inference]

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein urmylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein urmylation

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

tRNA wobble position uridine thiolation

tRNA thio-modification

tRNA wobble position uridine thiolation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytosolic tRNA wobble base thiouridylase complex	IBA
cytosol	ISS
cytosol	TAS
cytosol	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

cytosolic tRNA wobble base thiouridylase complex

catalytic complex [inference]

cytosolic tRNA wobble base thiouridylase complex

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
tRNA binding	IBA
protein binding	IPI	19017811 21209336
nucleotidyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

tRNA binding

Gene Ontology information from NCBI Gene and UniProt.

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Last updated: April 6, 2026

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