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Bcl2 modifying factor

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

90427

PubChem

90427

Alliance of Genome Resources

HGNC:24132

Annotation

Keyword

3D-structure
Alternative splicing
Apoptosis
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96LC9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
negative regulation of autophagy	IDA	23629966
negative regulation of autophagy	IBA
positive regulation of protein-containing complex assembly	ISS
cellular response to UV	IDA	23629966
positive regulation of apoptotic process	IMP	19671867

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

anoikis

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV [inference]

cellular response to UV

cellular response to light stimulus [inference]

cellular response to UV

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of mitochondrion organization [inference]

positive regulation of release of cytochrome c from mitochondria

positive regulation of protein-containing complex assembly

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of mitochondrion organization [inference]

positive regulation of release of cytochrome c from mitochondria

positive regulation of protein-containing complex assembly

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of mitochondrion organization [inference]

positive regulation of release of cytochrome c from mitochondria

regulation of mitochondrion organization [inference]

positive regulation of mitochondrion organization [inference]

positive regulation of release of cytochrome c from mitochondria

regulation of release of cytochrome c from mitochondria [inference]

positive regulation of release of cytochrome c from mitochondria

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of mitochondrion organization [inference]

positive regulation of release of cytochrome c from mitochondria

positive regulation of protein-containing complex assembly

Displaying **all 5** entries
GO Term	Evidence Code	PMID
mitochondrial outer membrane	TAS
cytosol	TAS
plasma membrane	TAS
myosin complex	ISS	11546872
myosin complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

myosin complex

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	11546872 25416956 26871637 31515488 32296183 32814053

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Bcl2 modifying factor

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
negative regulation of autophagy
positive regulation of apoptotic process

Displaying 1 entry
InterPro
Bcl-2-modifying factor

Ortholog

Displaying entries **1 - 10** of 56 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	90427	Xenbase:XB-GENE-982389
Mus musculus	171543		MOUSE35874
Rattus norvegicus	246142		RATNO26005
Pan troglodytes	453323		PANTR09959
Bos taurus	541141		BOVIN01002
Canis lupus familiaris	607313		CANLF12382
Macaca mulatta	706239		MACMU42702
Monodelphis domestica	100031831		MONDO05578
Taeniopygia guttata	100227756		TAEGU25071
Oryctolagus cuniculus	100357766		RABIT06189