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6-phosphogluconate dehydratase

Summary

Gene Symbol

Organism

Escherichia coli O157:H7 str. Sakai

External Links

NCBI Gene: 912867
PubChem: 912867

Annotation

Keyword

4Fe-4S
Carbohydrate metabolism
Gluconate utilization
Lyase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P0ADF7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
D-gluconate catabolic process
Entner-Doudoroff pathway through 6-phosphogluconate

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

Entner-Doudoroff pathway [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

pyruvate metabolic process [inference]

Entner-Doudoroff pathway [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

organophosphate metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

D-gluconate metabolic process [inference]

D-gluconate catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

Entner-Doudoroff pathway [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

pyruvate metabolic process [inference]

Entner-Doudoroff pathway [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

D-gluconate metabolic process [inference]

D-gluconate catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

Entner-Doudoroff pathway [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

pyruvate metabolic process [inference]

Entner-Doudoroff pathway [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organophosphate metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

carbohydrate derivative metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

Entner-Doudoroff pathway [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

pyruvate metabolic process [inference]

Entner-Doudoroff pathway [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

aldonic acid metabolic process [inference]

D-gluconate metabolic process [inference]

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

organophosphate metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

Entner-Doudoroff pathway through 6-phosphogluconate

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
4 iron, 4 sulfur cluster binding
metal ion binding
phosphogluconate dehydratase activity

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

phosphogluconate dehydratase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

metal cluster binding [inference]

iron-sulfur cluster binding [inference]

4 iron, 4 sulfur cluster binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:17277

6-phospho-D-gluconate

H₂O + 2-dehydro-3-deoxy-6-phospho-D-gluconate

Enzyme

4.2.1.12

PMID

14245409

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Acknowledgements