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LM-GlycoRepo

Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

autophagy related 12

Summary

Gene Symbol

ATG12

Organism

Homo sapiens (human)

External Links

NCBI Gene

9140

PubChem

9140

Alliance of Genome Resources

HGNC:588

JoGo

ATG12

TogoVar

ATG12

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
autophagosome assembly	ISS
autophagosome assembly	ISO
autophagosome assembly	IBA
autophagy of mitochondrion	IBA
macroautophagy	ISO

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion

nucleophagy [inference]

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion

nucleophagy [inference]

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion

nucleophagy [inference]

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

process utilizing autophagic mechanism [inference]

autophagy [inference]

autophagy of mitochondrion

nucleophagy [inference]

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

autophagy of mitochondrion

vacuole organization [inference]

autophagosome organization [inference]

autophagosome assembly

organelle assembly [inference]

autophagosome assembly

organelle disassembly [inference]

autophagy of mitochondrion

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

autophagosome maturation

organelle disassembly [inference]

autophagy of mitochondrion

cellular component assembly [inference]

organelle assembly [inference]

autophagosome assembly

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

autophagosome maturation

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of type I interferon production [inference]

negative regulation of type I interferon production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of catabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy [inference]

regulation of autophagosome maturation

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of type I interferon production [inference]

negative regulation of type I interferon production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy [inference]

regulation of autophagosome maturation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of type I interferon production [inference]

negative regulation of type I interferon production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

positive regulation of biological process [inference]

positive regulation of viral process [inference]

positive regulation of viral translation

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of defense response [inference]

negative regulation of response to external stimulus [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of defense response to virus [inference]

negative regulation of defense response to virus

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of defense response to virus [inference]

negative regulation of defense response to virus

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of defense response [inference]

negative regulation of response to external stimulus [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of defense response to virus [inference]

negative regulation of defense response to virus

regulation of viral process [inference]

positive regulation of viral process [inference]

positive regulation of viral translation

regulation of viral translation [inference]

positive regulation of viral translation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of type I interferon production [inference]

negative regulation of type I interferon production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy [inference]

regulation of autophagosome maturation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of autophagosome maturation

regulation of protein-containing complex disassembly [inference]

regulation of autophagosome maturation

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of type I interferon production [inference]

negative regulation of type I interferon production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
autophagosome membrane	IBA
nucleoplasm	IDA
autophagosome	IDA	24954904
cytosol	TAS
phagocytic vesicle membrane	TAS

GO Hierarchy

cellular component

protein-containing complex

catalytic complex [inference]

transferase complex

Atg12-Atg5-Atg16 complex

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

autophagosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

phagophore assembly site membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

autophagosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

autophagosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	11096062 11825910 20562859 23202584 24191030 25416956 26812546 32296183 33961781 35271311 9852036
Atg8-family ligase activity	IBA
protein tag activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-like protein ligase activity [inference]

Atg8-family ligase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-like protein ligase activity [inference]

Atg8-family ligase activity

binding [inference]

protein binding

molecular tag activity [inference]

protein tag activity

Gene Ontology information from NCBI Gene and UniProt.

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Last updated: April 6, 2026