GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

integrator complex subunit 4

Summary

Gene Symbol

INTS4

Organism

Homo sapiens (human)

External Links

NCBI Gene

92105

PubChem

92105

Alliance of Genome Resources

HGNC:25048

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Isopeptide bond
Nucleus
Proteomics identification
Reference proteome
Repeat
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A8Q3SHL8
A0A8Q3WKB5
Q96HW7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
snRNA processing	NAS	16239144
snRNA processing	IDA	16239144
snRNA processing	IBA
regulation of transcription elongation by RNA polymerase II	NAS	32697989

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

snRNA processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

ncRNA processing [inference]

snRNA processing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

snRNA processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

ncRNA processing [inference]

snRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

snRNA processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

ncRNA processing [inference]

snRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

snRNA processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

ncRNA processing [inference]

snRNA processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

snRNA processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

ncRNA processing [inference]

snRNA processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

snRNA processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

ncRNA processing [inference]

snRNA processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

snRNA processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

ncRNA processing [inference]

snRNA processing

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

snRNA processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

ncRNA processing [inference]

snRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

snRNA processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

ncRNA processing [inference]

snRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

snRNA processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

ncRNA processing [inference]

snRNA processing

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
nucleus	NAS	32647223
nucleus	IDA	23904267 39032490
nucleoplasm	TAS
nucleolus	IDA
integrator complex	NAS	33548203

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

integrator complex

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	16239144 25416956 26871637 31515488 32296183 33548203 33961781

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

integrator complex subunit 4

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
snRNA processing

Displaying **all 2** entries
InterPro
Armadillo-like helical
Armadillo-type fold

Ortholog

Displaying entries **1 - 10** of 91 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	92105	Xenbase:XB-GENE-5841108
Mus musculus	101861		MOUSE54032
Rattus norvegicus	308837		RATNO21141
Pan troglodytes	451444		PANTR03915
Canis lupus familiaris	476795		CANLF08232
Bos taurus	505657		BOVIN22877
Danio rerio	564681		DANRE14633
Macaca mulatta	699466		MACMU11411
Monodelphis domestica	100018147		MONDO21074
Taeniopygia guttata	100222075		TAEGU11230

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.4.0

Last updated: December 8, 2025