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CD9 molecule

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

928

PubChem

928

Alliance of Genome Resources

HGNC:1709

Annotation

Keyword

3D-structure
Cell adhesion
Cell membrane
Direct protein sequencing
Disulfide bond
Fertilization
Glycoprotein
Palmitate
Proteomics identification
Reference proteome
Secreted
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B4DK09
P21926	5H9 antigen Cell growth-inhibiting gene 2 protein Leukocyte antigen MIC3 Motility-related protein Tetraspanin-29 p24
A6NNI4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
cell adhesion	IDA	7511626
fusion of sperm to egg plasma membrane involved in single fertilization	IDA	14575715
cell population proliferation	IEA
negative regulation of cell population proliferation	IEA
glial cell migration	IMP	26224160

GO Hierarchy

biological process

cellular process [inference]

cell activation [inference]

platelet activation

syncytium formation [inference]

syncytium formation by plasma membrane fusion [inference]

myoblast fusion [inference]

myoblast fusion involved in skeletal muscle regeneration

cell adhesion

cell recognition [inference]

cell-cell recognition [inference]

sperm-egg recognition

cell population proliferation

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

cellular process involved in reproduction in multicellular organism [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

cell motility [inference]

cell migration [inference]

glial cell migration

cellular response to stimulus [inference]

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

paranodal junction assembly

cell junction assembly [inference]

cell-cell junction assembly [inference]

paranodal junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

paranodal junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

paranodal junction assembly

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane fusion [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

membrane fusion [inference]

plasma membrane fusion [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

cell-cell fusion [inference]

syncytium formation by plasma membrane fusion [inference]

myoblast fusion [inference]

myoblast fusion involved in skeletal muscle regeneration

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

sperm-egg recognition

multicellular organismal process [inference]

cell activation [inference]

platelet activation

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

syncytium formation [inference]

syncytium formation by plasma membrane fusion [inference]

myoblast fusion [inference]

myoblast fusion involved in skeletal muscle regeneration

cellular component assembly involved in morphogenesis [inference]

paranodal junction assembly

response to stimulus [inference]

response to endogenous stimulus [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

cellular response to stimulus [inference]

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte migration [inference]

regulation of macrophage migration

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of macrophage migration

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of homotypic cell-cell adhesion [inference]

negative regulation of platelet aggregation

negative regulation of cell population proliferation

negative regulation of cell activation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of multicellular organismal process [inference]

negative regulation of coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of cell activation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of hemostasis [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

regulation of response to stress [inference]

regulation of response to wounding [inference]

regulation of wound healing [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

regulation of cellular process [inference]

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of homotypic cell-cell adhesion [inference]

negative regulation of platelet aggregation

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of homotypic cell-cell adhesion [inference]

negative regulation of platelet aggregation

regulation of homotypic cell-cell adhesion [inference]

negative regulation of homotypic cell-cell adhesion [inference]

negative regulation of platelet aggregation

regulation of platelet aggregation [inference]

negative regulation of platelet aggregation

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of homotypic cell-cell adhesion [inference]

negative regulation of platelet aggregation

negative regulation of cell population proliferation

negative regulation of cell activation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

regulation of cell activation [inference]

regulation of platelet activation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

regulation of platelet aggregation [inference]

negative regulation of platelet aggregation

negative regulation of cell activation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of macrophage migration

regulation of multicellular organismal process [inference]

regulation of coagulation [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

regulation of cell activation [inference]

regulation of platelet activation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

regulation of platelet aggregation [inference]

negative regulation of platelet aggregation

negative regulation of cell activation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of multicellular organismal process [inference]

negative regulation of coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of cell activation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

regulation of hemostasis [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of hemostasis [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

regulation of biological quality [inference]

regulation of body fluid levels [inference]

regulation of hemostasis [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

negative regulation of hemostasis [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation [inference]

negative regulation of platelet aggregation

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
extracellular space	HDA	16502470
plasma membrane	ISS
plasma membrane	NAS	2037603
plasma membrane	TAS
plasma membrane	IBA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

extracellular space

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

coated vesicle membrane [inference]

clathrin-coated vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

endocytic vesicle membrane

clathrin-coated endocytic vesicle membrane

secretory granule membrane [inference]

platelet alpha granule membrane

bounding membrane of organelle [inference]

coated vesicle membrane [inference]

clathrin-coated vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

endocytic vesicle membrane

clathrin-coated endocytic vesicle membrane

secretory granule membrane [inference]

platelet alpha granule membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
integrin binding	IDA	12796480 27993971
protein binding	IPI	11278880 11504738 12796480 15344881 18541721 23091066 23289620 23858057 26686862 30833792 32296183 35271311

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Tetraspanin

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
Tetraspanin, EC2 domain superfamily
Tetraspanin, animals
Tetraspanin, conserved site
Tetraspanin/Peripherin

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2526	prostate adenocarcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **121** in total

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Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	928	Xenbase:XB-GENE-949525
Xenopus tropicalis	6317	Xenbase:XB-GENE-949525
Caenorhabditis elegans	7103	WB:WBGene00006632
Caenorhabditis elegans	7106	WB:WBGene00006632
Drosophila melanogaster	10100	FB:FBgn0027865
Caenorhabditis elegans	10103	WB:WBGene00006632
Caenorhabditis elegans	10867	WB:WBGene00006632
Drosophila melanogaster	12493	FB:FBgn0027865
Drosophila melanogaster	12512	FB:FBgn0032943
Drosophila melanogaster	12520	FB:FBgn0027865

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements