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MIRAGE
matrix metallopeptidase 20
Summary
- Gene Symbol
-
- MMP20
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Amelogenesis imperfecta
- Autocatalytic cleavage
- Calcium
- Disulfide bond
- Extracellular matrix
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| O60882 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| extracellular matrix disassembly | ||
| protein catabolic process | ||
| extracellular matrix organization | ||
| collagen catabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular matrix |
| GO Term | Evidence Code | PMID |
|---|---|---|
| metalloendopeptidase activity | ||
| metalloendopeptidase activity | ||
| protein binding | ||
| zinc ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- matrix metalloproteinase
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| collagen catabolic process |
| extracellular matrix organization |
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| zinc ion binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110060 | amelogenesis imperfecta hypomaturation type 2A2 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 4312 | WB:WBGene00016283 | ||
| 4314 | WB:WBGene00016283 | ||
| 4317 | WB:WBGene00016283 | ||
| 4321 | WB:WBGene00016283 | ||
| 4322 | WB:WBGene00020646 | ||
| 4323 | WB:WBGene00010423 | ||
| 4324 | WB:WBGene00010423 | ||
| 4325 | WB:WBGene00010423 | ||
| 4326 | WB:WBGene00010423 | ||
| 4327 | WB:WBGene00016283 |
