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MIRAGE
heparan sulfate 6-O-sulfotransferase 1
Summary
- Gene Symbol
-
- HS6ST1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Coiled coil
- Disease variant
- Glycoprotein
- Hypogonadotropic hypogonadism
- Kallmann syndrome
- Reference proteome
- Signal-anchor
- Transferase
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O60243 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| angiogenesis | ||
| heparan sulfate proteoglycan biosynthetic process, enzymatic modification | ||
| heparan sulfate proteoglycan biosynthetic process, enzymatic modification | ||
| lung alveolus development | ||
| neuron development |
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| sulfotransferase activity | ||
| heparan sulfate 6-O-sulfotransferase activity | ||
| heparan sulfate 6-O-sulfotransferase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Heparan sulfate 6-O-sulfotransferase
- Functional Category
-
- G: Carbohydrate transport and metabolism
- H: Coenzyme transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
| Gene Ontology |
|---|
| heparan sulfate 6-O-sulfotransferase activity |
| heparan sulfate proteoglycan biosynthetic process, enzymatic modification |
| sulfotransferase activity |
| transferase activity |
| InterPro |
|---|
| Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase |
| P-loop containing nucleoside triphosphate hydrolase |
| Sulfotransferase |
GlycoGene Database (GGDB)
- GGDB ID
- gg031
- Gene Symbol
-
- HS6ST1
- Orthologous Gene
| Species | Protein | mRNA |
|---|---|---|
| Drosophila melanogaster | NP_524409 | NM_079685 |
| Caenorhabditis elegans | NP_508895 | NM_076494 |
| Mus musculus | NP_056633 | NM_015818 |
| Rattus norvegicus | XP_237060 | XM_237060 |
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0090075 | hypogonadotropic hypogonadism 15 with or without anosmia |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000002 | Abnormality of body height |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0000008 | Abnormal morphology of female internal genitalia |
| HP:0000013 | Hypoplasia of the uterus |
| HP:0000026 | Male hypogonadism |
| HP:0000027 | Azoospermia |
| HP:0000028 | Cryptorchidism |
| HP:0000044 | Hypogonadotropic hypogonadism |
| HP:0000054 | Micropenis |
| HP:0000104 | Renal agenesis |
| Disease ID | Disease Name |
|---|---|
| ORPHA:432 |
|
| OMIM:614880 |
|
| ORPHA:478 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101563722 | OCTDE03720 | ||
| 101609516 | JACJA19987 | ||
| 101693571 | MUSPF01669 | ||
| 101807511 | FICAL10235 | ||
| 101964422 | ICTTR10146 | ||
| 102017850 | CHILA15029 | ||
| 102356920 | LATCH13968 | ||
| 102418297 | MYOLU14501 | ||
| 103174702 | CALMI00954 | ||
| 103216864 | CHLSB01209 |
