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core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1

Summary

Gene Symbol

C1galt1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

94192

KEGG Gene ID

mmu:94192

PubChem

94192

Alliance of Genome Resources

MGI:2151071

Annotation

Keyword

Angiogenesis
Developmental protein
Differentiation
Disulfide bond
Glycosyltransferase
Manganese
Metal-binding
Nucleotide-binding
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JJ06	Core 1 O-glycan T-synthase Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1 Core 1 beta1,3-galactosyltransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
O-glycan processing, core 1	IBA ISO	11677243
protein O-linked glycosylation	IMP	21383503
angiogenesis	IMP ISO	14745002
kidney development	ISO
multicellular organism development	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing [inference]

O-glycan processing, core 1

cellular process [inference]

cellular developmental process [inference]

cell differentiation

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

intestinal epithelial cell development

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

multicellular organism development

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

intestinal epithelial cell development

animal organ development [inference]

kidney development

cellular developmental process [inference]

cell differentiation

cell development [inference]

epithelial cell development [inference]

columnar/cuboidal epithelial cell development [inference]

intestinal epithelial cell development

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

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GO Term	Evidence Code	PMID
glycosyltransferase activity	IEA
transferase activity	IEA
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	IBA ISO
galactosyltransferase activity	ISO	11677243
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

hexosyltransferase activity [inference]

galactosyltransferase activity

beta-1,3-galactosyltransferase activity [inference]

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

ion binding [inference]

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00731

Name

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122]

References

11677243

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05908	2.4.1.122	G57321FI	G00031MO

Rhea

RHEA:15621

an N-acetyl-α-D-galactosaminyl derivative + UDP-α-D-galactose

a β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + H⁺ + UDP

Enzyme

2.4.1.122

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060050	autoimmune disease of blood	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	176455	WB:WBGene00008019
Drosophila melanogaster	32896	FB:FBgn0030984
Drosophila melanogaster	33482	FB:FBgn0031469
Drosophila melanogaster	33485	FB:FBgn0031472
Drosophila melanogaster	34215	FB:FBgn0032078
Drosophila melanogaster	35792	FB:FBgn0033271
Callorhinchus milii	103185987		CALMI33593
Latimeria chalumnae	102345499		LATCH11102
Lepisosteus oculatus	102690951		LEPOC02736
Danio rerio	337131	ZFIN:ZDB-GENE-030131-9075

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements