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Guidelines

MIRAGE

protein tyrosine phosphatase, receptor type, R

Summary

Gene Symbol

Ptprr

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

94202

PubChem

94202

Alliance of Genome Resources

RGD:620780

Annotation

Keyword

Alternative splicing
Cell membrane
Cytoplasm
Phosphoprotein
Protein phosphatase
Proteoglycan
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
G3V6L5
O08617	PC12-PTP1 Protein-tyrosine phosphatase PCPTP1 Tyrosine phosphatase CBPTP
A6IGM0
Q5FWV8

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
neuron differentiation	IEP	7814416
protein dephosphorylation	ISO
signal transduction	IBA
ERBB2 signaling pathway	IEA ISO
chromatin remodeling	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

ERBB2 signaling pathway

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of epithelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

negative regulation of epithelial cell migration

negative regulation of cell migration [inference]

negative regulation of epithelial cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of epithelial cell migration

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of epithelial cell migration

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of epithelial cell migration

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of multicellular organismal process [inference]

negative regulation of epithelial cell migration

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

ERBB2 signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

regulation of homophilic cell adhesion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of epithelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

negative regulation of epithelial cell migration

negative regulation of cell migration [inference]

negative regulation of epithelial cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of epithelial cell migration

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

negative regulation of epithelial cell migration

negative regulation of multicellular organismal process [inference]

negative regulation of epithelial cell migration

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA IEA ISO
cytosol	IBA IEA ISO
cell junction	IBA IEA ISO
endomembrane system	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction

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GO Term	Evidence Code	PMID
protein kinase binding	IBA IEA ISO
non-membrane spanning protein tyrosine phosphatase activity	IEA
protein tyrosine phosphatase activity	IBA ISO TAS	7814416
protein binding	IPI	12526090
histone H2AXY142 phosphatase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

histone modifying activity [inference]

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **1 - 10** of 61 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	5778	FB:FBgn0016641
Homo sapiens	5801	Xenbase:XB-GENE-961693	HUMAN14304
Drosophila melanogaster	19259	FB:FBgn0016641
Mus musculus	19279	Xenbase:XB-GENE-961693	MOUSE01551
Xenopus tropicalis	94202	Xenbase:XB-GENE-961693
Pan troglodytes	452076		PANTR06409
Canis lupus familiaris	481163		CANLF01423
Bos taurus	536337		BOVIN29410
Macaca mulatta	718582		MACMU04753
Monodelphis domestica	100015968		MONDO34354

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Last updated: February 17, 2025