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solute carrier family 4, sodium bicarbonate cotransporter-like, member 10

Summary

Gene Symbol

Slc4a10

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

94229

PubChem

94229

Alliance of Genome Resources

MGI:2150150

Annotation

Keyword

Alternative promoter usage
Alternative splicing
Antiport
Cell membrane
Cell projection
Glycoprotein
Ion transport
Phosphoprotein
Reference proteome
Sodium transport
Symport
Synapse
Transmembrane helix
Zinc

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q8C943
Q5DTL9	Solute carrier family 4 member 10
B1AWV9
R4H243

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 20 in total

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GO Term	Evidence Code	PMID
regulation of intracellular pH	IBA
post-embryonic development	IMP	18165320
regulation of pH	IDA	10993873
visual perception	IMP	23056253
sodium ion transmembrane transport	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

cellular process [inference]

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

central nervous system neuron development [inference]

forebrain neuron development [inference]

pyramidal neuron development

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

monoatomic anion transmembrane transport

inorganic ion transmembrane transport

inorganic cation transmembrane transport [inference]

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

behavior [inference]

locomotory behavior [inference]

locomotory exploration behavior

exploration behavior [inference]

locomotory exploration behavior

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

brain morphogenesis

anatomical structure development [inference]

cell development [inference]

neuron development [inference]

central nervous system neuron development [inference]

forebrain neuron development [inference]

pyramidal neuron development

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

central nervous system neuron development [inference]

forebrain neuron development [inference]

pyramidal neuron development

growth [inference]

developmental growth [inference]

multicellular organism growth

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

regulation of intracellular pH

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

regulation of intracellular pH

monoatomic cation homeostasis [inference]

regulation of pH

regulation of cellular pH

regulation of intracellular pH

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

regulation of intracellular pH

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

regulation of intracellular pH

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

monoatomic anion transport [inference]

monoatomic anion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

monoatomic anion transmembrane transport

inorganic anion transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

monoatomic anion transmembrane transport

inorganic ion transmembrane transport

inorganic cation transmembrane transport [inference]

organic substance transport [inference]

organic anion transport [inference]

bicarbonate transport

one-carbon compound transport [inference]

bicarbonate transport

biological regulation [inference]

regulation of pH

regulation of cellular pH

regulation of intracellular pH

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of short-term neuronal synaptic plasticity

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of short-term neuronal synaptic plasticity

regulation of biological quality

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of short-term neuronal synaptic plasticity

regulation of intracellular pH

Displaying entries **11 - 15** of 15 in total

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GO Term	Evidence Code	PMID
basolateral plasma membrane	IBA IDA ISO	14592810 18061361 20541593 21705333
apical dendrite	IDA	18165320
somatodendritic compartment	IDA	24905082
synapse	IDA	26136660
GABA-ergic synapse	IDA	37459438

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

lateral plasma membrane

cell junction [inference]

synapse

GABA-ergic synapse

somatodendritic compartment

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

perikaryon

cell body [inference]

neuronal cell body

neuron projection terminus [inference]

axon terminus

presynapse [inference]

axon terminus

postsynapse

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
monoatomic anion transmembrane transporter activity
sodium:bicarbonate symporter activity	IBA IDA ISO	20566632
active monoatomic ion transmembrane transporter activity
bicarbonate transmembrane transporter activity
sodium,bicarbonate:chloride antiporter activity	IDA ISO	10993873 20566632

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

sodium,bicarbonate:chloride antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

monoatomic anion transmembrane transporter activity

chloride transmembrane transporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

active monoatomic ion transmembrane transporter activity

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

metal cation:monoatomic cation antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

solute:inorganic anion antiporter activity

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

chloride transmembrane transporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

bicarbonate transmembrane transporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

sodium,bicarbonate:chloride antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

antiporter activity [inference]

solute:inorganic anion antiporter activity

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

active monoatomic ion transmembrane transporter activity

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

metal cation:monoatomic cation antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

sodium,bicarbonate:chloride antiporter activity

bicarbonate transmembrane transporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

chloride transmembrane transporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

sodium-driven chloride bicarbonate exchanger

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
inorganic anion transport
monoatomic anion transmembrane transporter activity
monoatomic ion transport
regulation of intracellular pH
sodium
solute

Displaying **all 5** entries
InterPro
Band 3 cytoplasmic domain
Bicarbonate transporter, eukaryotic
Bicarbonate transporter-like, transmembrane domain
Phosphotransferase/anion transporter
Sodium bicarbonate cotransporter

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2355	anemia	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of **117** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Loxodonta africana	100663493		LOXAF19005
Cavia porcellus	100721375	10141_0:0047c4	CAVPO02097
Cricetulus griseus	100766143	10029_0:003ca2
Sarcophilus harrisii	100934423		SARHA10726
Otolemur garnettii	100957146		OTOGA07507
Pan paniscus	100983790		PANPA25935
Papio anubis	101025328		PAPAN01661
Saimiri boliviensis boliviensis	101042220		SAIBB03674
Felis catus	101098732		FELCA19309
Ovis aries	101107575		SHEEP09472

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements