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solute carrier family 4, sodium bicarbonate cotransporter-like, member 10

Summary

Gene Symbol

Slc4a10

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

94229

PubChem

94229

Alliance of Genome Resources

MGI:2150150

Annotation

Keyword

Alternative promoter usage
Alternative splicing
Antiport
Cell membrane
Cell projection
Glycoprotein
Ion transport
Phosphoprotein
Reference proteome
Sodium transport
Symport
Synapse
Transmembrane helix
Zinc

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q8C943
Q5DTL9	Solute carrier family 4 member 10
B1AWV9
R4H243

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
inorganic ion transmembrane transport
regulation of cellular pH	IMP	18165320
multicellular organism growth	IMP	18165320
brain morphogenesis	IMP	18165320
protein glycosylation	ISO	14592810

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

cellular process [inference]

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

central nervous system neuron development [inference]

forebrain neuron development [inference]

pyramidal neuron development

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

monoatomic anion transmembrane transport

inorganic ion transmembrane transport

inorganic cation transmembrane transport [inference]

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

behavior [inference]

locomotory behavior [inference]

locomotory exploration behavior

exploration behavior [inference]

locomotory exploration behavior

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

brain morphogenesis

anatomical structure development [inference]

cell development [inference]

neuron development [inference]

central nervous system neuron development [inference]

forebrain neuron development [inference]

pyramidal neuron development

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

central nervous system neuron development [inference]

forebrain neuron development [inference]

pyramidal neuron development

growth [inference]

developmental growth [inference]

multicellular organism growth

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

regulation of intracellular pH

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

regulation of intracellular pH

monoatomic cation homeostasis [inference]

regulation of pH

regulation of cellular pH

regulation of intracellular pH

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

regulation of intracellular pH

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

regulation of intracellular pH

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

monoatomic anion transport [inference]

monoatomic anion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

monoatomic anion transmembrane transport

inorganic anion transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

monoatomic anion transmembrane transport

inorganic ion transmembrane transport

inorganic cation transmembrane transport [inference]

organic substance transport [inference]

organic anion transport [inference]

bicarbonate transport

one-carbon compound transport [inference]

bicarbonate transport

biological regulation [inference]

regulation of pH

regulation of cellular pH

regulation of intracellular pH

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of short-term neuronal synaptic plasticity

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of short-term neuronal synaptic plasticity

regulation of biological quality

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of short-term neuronal synaptic plasticity

regulation of intracellular pH

Displaying entries **11 - 15** of 15 in total

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GO Term	Evidence Code	PMID
basolateral plasma membrane	IBA IDA ISO	14592810 18061361 20541593 21705333
apical dendrite	IDA	18165320
somatodendritic compartment	IDA	24905082
synapse	IDA	26136660
GABA-ergic synapse	IDA	37459438

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

lateral plasma membrane

cell junction [inference]

synapse

GABA-ergic synapse

somatodendritic compartment

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

perikaryon

cell body [inference]

neuronal cell body

neuron projection terminus [inference]

axon terminus

presynapse [inference]

axon terminus

postsynapse

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
monoatomic anion transmembrane transporter activity
sodium:bicarbonate symporter activity	IBA IDA ISO	20566632
active monoatomic ion transmembrane transporter activity
bicarbonate transmembrane transporter activity
sodium,bicarbonate:chloride antiporter activity	IDA ISO	10993873 20566632

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

sodium,bicarbonate:chloride antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

monoatomic anion transmembrane transporter activity

chloride transmembrane transporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

active monoatomic ion transmembrane transporter activity

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

metal cation:monoatomic cation antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

solute:inorganic anion antiporter activity

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

chloride transmembrane transporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

bicarbonate transmembrane transporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

sodium,bicarbonate:chloride antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

antiporter activity [inference]

solute:inorganic anion antiporter activity

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

active monoatomic ion transmembrane transporter activity

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

metal cation:monoatomic cation antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:bicarbonate symporter activity

sodium,bicarbonate:chloride antiporter activity

bicarbonate transmembrane transporter activity

monoatomic cation:bicarbonate symporter activity [inference]

sodium:bicarbonate symporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

chloride transmembrane transporter activity [inference]

chloride:bicarbonate antiporter activity [inference]

sodium,bicarbonate:chloride antiporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

sodium-driven chloride bicarbonate exchanger

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
inorganic anion transport
monoatomic anion transmembrane transporter activity
monoatomic ion transport
regulation of intracellular pH
sodium
solute

Displaying **all 5** entries
InterPro
Band 3 cytoplasmic domain
Bicarbonate transporter, eukaryotic
Bicarbonate transporter-like, transmembrane domain
Phosphotransferase/anion transporter
Sodium bicarbonate cotransporter

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2355	anemia	Alliance of Genome Resources

Ortholog

Displaying entries **71 - 80** of **117** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Ictalurus punctatus	108270744		ICTPU01747
Pygocentrus nattereri	108412979		PYGNA33693
Pygocentrus nattereri	108424319		PYGNA05312
Cyprinus carpio carpio	109072596		CYPCA51810
Cyprinus carpio carpio	109091295		CYPCA119051
Castor canadensis	109696969	51338_0:00377e
Mus caroli	110306050	10089_0:00066c
Mus pahari	110317889	10093_0:001320
Urocitellus parryii	113185854	9999_0:0019c4
Athene cunicularia	113482192		ATHCN08753

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements