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PBP1Bgamma;peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcB

Summary

Gene Symbol

mrcB

Organism

Escherichia coli str. K-12 substr. MG1655

External Links

NCBI Gene: 944843
KEGG Gene ID: eco:b0149
PubChem: 944843

Annotation

Keyword

3D-structure
Alternative initiation
Antibiotic resistance
Carboxypeptidase
Cell inner membrane
Cell wall biogenesis/degradation
Direct protein sequencing
Glycosyltransferase
Multifunctional enzyme
Peptidoglycan synthesis
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P02919	Murein polymerase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
peptidoglycan biosynthetic process	IEA
response to antibiotic	IMP	345275
response to antibiotic	IEA
positive regulation of bipolar cell growth	IDA	330236
cell wall repair	IDA	31904338

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

protein metabolic process [inference]

proteolysis

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

protein metabolic process [inference]

proteolysis

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan biosynthetic process

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

protein metabolic process [inference]

proteolysis

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall macromolecule biosynthetic process [inference]

peptidoglycan biosynthetic process

cell wall organization or biogenesis [inference]

cell wall organization

cell wall repair

cellular component organization or biogenesis [inference]

cellular component organization [inference]

external encapsulating structure organization [inference]

cell wall organization

cell wall repair

response to stimulus [inference]

response to chemical [inference]

response to antibiotic

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of unidimensional cell growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of bipolar cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of developmental growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of developmental growth [inference]

positive regulation of developmental growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of unidimensional cell growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of bipolar cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of biological process [inference]

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of developmental growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of cellular process [inference]

positive regulation of cell growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of developmental growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

positive regulation of cell morphogenesis [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of unidimensional cell growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of bipolar cell growth [inference]

positive regulation of bipolar cell growth

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of developmental growth [inference]

positive regulation of developmental growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of unidimensional cell growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of bipolar cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of developmental growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of cellular process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of cellular process [inference]

positive regulation of cell growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of unidimensional cell growth [inference]

positive regulation of unidimensional cell growth [inference]

positive regulation of bipolar cell growth

regulation of bipolar cell growth [inference]

positive regulation of bipolar cell growth

regulation of biological quality [inference]

regulation of cell shape

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	IDA	3330753
plasma membrane	IEA
peptidoglycan-based cell wall	IEA
membrane	HDA	16858726
outer membrane-bounded periplasmic space	IDA	3330753

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

external encapsulating structure [inference]

cell wall [inference]

peptidoglycan-based cell wall

periplasmic space [inference]

outer membrane-bounded periplasmic space

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
carboxypeptidase activity	IEA
protein binding	IPI	10542235 16803586 17938168 18165305 19458048 21183073 21183074 25951518 30723128 31015395 33144379 9158739
peptidase activity	IEA
penicillin binding	IDA	10564478 345275
penicillin binding	IEA