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Guidelines

MIRAGE

methylglyoxal reductase DkgB

Summary

Gene Symbol

dkgB

Organism

Escherichia coli str. K-12 substr. MG1655

External Links

NCBI Gene: 944901
PubChem: 944901

Annotation

Keyword

Ascorbate biosynthesis
Cytoplasm
NADP
Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P30863	AKR5D

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
L-ascorbic acid biosynthetic process	IEA
methylglyoxal catabolic process	IMP	16077126
methylglyoxal catabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process

aldehyde catabolic process [inference]

methylglyoxal catabolic process

small molecule catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process

organic substance catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process

aldehyde catabolic process [inference]

methylglyoxal catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process

aldehyde catabolic process [inference]

methylglyoxal catabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process

ketone catabolic process [inference]

methylglyoxal catabolic process

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process

aldehyde catabolic process [inference]

methylglyoxal catabolic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process

ketone catabolic process [inference]

methylglyoxal catabolic process

small molecule catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process

aldehyde catabolic process [inference]

methylglyoxal catabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process

ketone catabolic process [inference]

methylglyoxal catabolic process

organic cyclic compound metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic substance catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process

aldehyde catabolic process [inference]

methylglyoxal catabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process

aldehyde catabolic process [inference]

methylglyoxal catabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process

ketone catabolic process [inference]

methylglyoxal catabolic process

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process

aldehyde catabolic process [inference]

methylglyoxal catabolic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
aldo-keto reductase (NADP) activity	IDA	10427017
aldo-keto reductase (NADP) activity	IBA
oxidoreductase activity	IEA
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA
aryl-alcohol dehydrogenase (NADP+) activity	IDA	16813561

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Gene Ontology information from NCBI Gene and UniProt.

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025