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isocitrate dehydrogenase

Summary

Gene Symbol

icd

Organism

Escherichia coli str. K-12 substr. MG1655

External Links

NCBI Gene: 945702
PubChem: 945702

Annotation

Keyword

3D-structure
Acetylation
Direct protein sequencing
Glyoxylate bypass
Magnesium
Manganese
Metal-binding
NADP
Oxidoreductase
Phosphoprotein
Reference proteome
Tricarboxylic acid cycle

Proteins

Displaying 1 entry
UniProt	Protein Name
P08200	IDP NADP(+)-specific ICDH Oxalosuccinate decarboxylase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
response to oxidative stress	IMP	24580753
glyoxylate cycle	IEA
electron transport chain	IMP	15221231 776950
tricarboxylic acid cycle	IDA IEA	4932752

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

generation of precursor metabolites and energy [inference]

electron transport chain

primary metabolic process [inference]

carbohydrate metabolic process [inference]

glyoxylate cycle

tricarboxylic acid cycle

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

glyoxylate cycle

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

generation of precursor metabolites and energy [inference]

electron transport chain

response to stimulus [inference]

response to stress [inference]

response to oxidative stress

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IDA	15911532 18304323
cytoplasm	IDA	34215

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
oxidoreductase activity	IEA
magnesium ion binding	IEA
NAD binding	IEA
metal ion binding	IEA
protein binding	IPI	20505668 24561554

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

isocitrate dehydrogenase [NAD(P)+] activity [inference]

isocitrate dehydrogenase (NADP+) activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

guanosine tetraphosphate binding

adenyl nucleotide binding [inference]

NAD binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

guanosine tetraphosphate binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

guanosine tetraphosphate binding

ion binding [inference]

anion binding [inference]

guanosine tetraphosphate binding

cation binding [inference]

metal ion binding

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

guanosine tetraphosphate binding

adenyl nucleotide binding [inference]

NAD binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

guanosine tetraphosphate binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

guanosine tetraphosphate binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

guanosine tetraphosphate binding

Gene Ontology information from NCBI Gene and UniProt.

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Last updated: August 19, 2024

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